Аннотация:
Novel purin-6-yl, 2-aminopurin-6-yl and N-(purin-6-yl)glycyl derivatives of (S)-lysine and (S)-ornithine with free α-functional groups, as well as compounds containing N9-(2-hydroxy-ethoxy)methyl substituent in the purine core have been synthesized and tested for their inhibitory effect against Mycobacterium tuberculosis strains. Among the synthesized conjugates, one compound exhibiting a significant level of antimycobacterial activity has been found.
Образец цитирования:
V. V. Musiyak, D. A. Gruzdev, M. A. Kravchenko, D. V. Vakhrusheva, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Synthesis and antimycobacterial activity of purine conjugates with (S)-lysine and (S)-ornithine”, Mendeleev Commun., 29:1 (2019), 11–13
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc1404
https://www.mathnet.ru/rus/mendc/v29/i1/p11
Эта публикация цитируется в следующих 11 статьяx:
A. A. Telegina, D. A. Gruzdev, G. L. Levit, V. P. Krasnov, “Synthesis of new nido-carborane-containing 6-thiopurine derivatives”, Russ Chem Bull, 72:12 (2023), 2860
Barbara Z. Eletskaya, Maria Ya. Berzina, Ilya V. Fateev, Alexei L. Kayushin, Elena V. Dorofeeva, Olga I. Lutonina, Ekaterina A. Zorina, Konstantin V. Antonov, Alexander S. Paramonov, Inessa S. Muzyka, Olga S. Zhukova, Mikhail V. Kiselevskiy, Anatoly I. Miroshnikov, Roman S. Esipov, Irina D. Konstantinova, “Enzymatic Synthesis of 2-Chloropurine Arabinonucleosides with Chiral Amino Acid Amides at the C6 Position and an Evaluation of Antiproliferative Activity In Vitro”, IJMS, 24:7 (2023), 6223
Maria Ya. Berzina, Barbara Z. Eletskaya, Alexei L. Kayushin, Elena V. Dorofeeva, Olga I. Lutonina, Ilya V. Fateev, Alexander S. Paramonov, Maria A. Kostromina, Evgeniy A. Zayats, Yulia A. Abramchik, Dmitriy V. Maltsev, Ludmila V. Naumenko, Alena S. Taran, Dmitry S. Yakovlev, Alexander A. Spasov, Anatoly I. Miroshnikov, Roman S. Esipov, Irina D. Konstantinova, “Synthesis of 2-chloropurine ribosides with chiral amino acid amides at C6 and their evaluation as A1 adenosine receptor agonists”, Bioorganic Chemistry, 126 (2022), 105878
A. Yu. Vigorov, E. B. Gorbunov, M. A. Ezhikova, M. I. Kodess, D. V. Belyaev, D. V. Vakhrusheva, G. L. Levit, V. P. Krasnov, “Synthesis of purine conjugates with N-(4-aminobenzenesulfonyl)-and N-(2-aminoethanesulfonyl)-(S)-glutamic acids”, Russ Chem Bull, 71:12 (2022), 2685
A. A. Telegina, D. A. Gruzdev, G. L. Levit, V. P. Krasnov, “Synthesis of new conjugates of 6-thiopurine and thioguanine with (S)-glutamic acid”, Russ Chem Bull, 71:11 (2022), 2426
Armands Sebris, Kaspars Traskovskis, Irina Novosjolova, Māris Turks, “Synthesis and photophysical properties of 2-azolyl-6-piperidinylpurines”, Chem Heterocycl Comp, 57:5 (2021), 560
Olga А. Vozdvizhenskaya, Valeriya L. Andronova, Georgii А. Galegov, Galina L. Levit, Victor P. Krasnov, Valery N. Charushin, “Synthesis and antiherpetic activity of novel purine conjugates with 7,8-difluoro-3-methyl-3,4-dihydro-2H-1,4-benzoxazine”, Chem Heterocycl Comp, 57:4 (2021), 490
Victor P. Krasnov, Galina L. Levit, Vera V. Musiyak, Dmitry A. Gruzdev, Valery N. Charushin, “Fragment-based approach to novel bioactive purine derivatives”, Pure and Applied Chemistry, 92:8 (2020), 1277
Ammar Sheykhi-Estalkhjani, Nosrat O. Mahmoodi, Asieh Yahyazadeh, Meysam Pasandideh Nadamani, “Synthesis and antibacterial evaluation of diaminomaleonitrile-based azo-Schiff bases and 8,9-dihydro-7H-purine-6-carboxamides”, Res Chem Intermed, 46:8 (2020), 3835
E. V. Verbitskiy, G. L. Rusinov, V. N. Charushin, O. N. Chupakhin, “Development of new antituberculosis drugs among of 1,3- and 1,4-diazines. Highlights and perspectives”, Russ Chem Bull, 68:12 (2019), 2172
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