Аннотация:
New glycosylated alkyl glycerolipids bearing a cationic group at the C6 position of sugar moiety have been synthesized and tested as potential anticancer drugs. The compounds demonstrated cytotoxicity and selectivity against tumor cells at low micromolar concentration.
Образец цитирования:
N. G. Morozova, E. V. Shmendel, G. A. Timofeev, I. V. Ivanov, T. S. Kubasova, N. V. Plyavnik, A. A. Markova, M. A. Maslov, A. A. Shtil, “New design of cationic alkyl glycoglycerolipids toxic to tumor cells”, Mendeleev Commun., 29:2 (2019), 166–168
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc1458
https://www.mathnet.ru/rus/mendc/v29/i2/p166
Эта публикация цитируется в следующих 4 статьяx:
Arseny D. Moralev, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Andrey V. Markov, “Soloxolone N-3-(Dimethylamino)propylamide Restores Drug Sensitivity of Tumor Cells with Multidrug-Resistant Phenotype via Inhibition of P-Glycoprotein Efflux Function”, Molecules, 29:20 (2024), 4939
Marco Antônio G B Gomes, Alicia Bauduin, Chloé Le Roux, Romain Fouinneteau, Wilfried Berthe, Mathieu Berchel, Hélène Couthon, Paul-Alain Jaffrès, “Synthesis of ether lipids: natural compounds and analogues”, Beilstein J. Org. Chem., 19 (2023), 1299
E. A. Varlamova, A. K. Isagulieva, N. G. Morozova, E. V. Shmendel, M. A. Maslov, A. A. Shtil, “Non-Phosphorus Lipids As New Antitumor Drug Prototypes”, Russ J Bioorg Chem, 47:5 (2021), 965
A. I. Nichugovskiy, A. A. Khrulev, K. A. Perevoshchikova, D. A. Cheshkov, N. G. Morozova, M. A. Maslov, “Synthesis of Isonitrile Derivatives of Diglycerides and Carbohydrates as Intermediates for Multicomponent Ugi Reaction”, Russ J Bioorg Chem, 47:4 (2021), 929
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