|
Эта публикация цитируется в 3 научных статьях (всего в 3 статьях)
Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties
U. M. Dzhemilev, A. R. Akhmetov, V. A. D'yakonov, L. U. Dzhemileva, M. M. Yunusbaeva, A. R. Tuktarov
Institute of Petrochemistry and Catalysis, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
Аннотация:
Hybrids composed of 3-pentylnorbornadiene-2-carboxylic acid or its quadricyclane isomer molecules linked to methano-C60 fullerene via triethylene glycol spacer were synthesized by the Bingel–Hirsch reaction. The quadricyclane derivative possesses markedly higher apoptosis-inducing activity against the Jurkat tumor cells than the norbornadiene one.
Ключевые слова:
C60 fullerene, norbornadiene, quadricyclane, methanofullerenes, cytotoxic activity.
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc1130
|
|
Обратная связь: