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Эта публикация цитируется в 7 научных статьях (всего в 7 статьях)
Asymmetric aldol reaction of isatins with acetone in the presence of terpene amino alcohols
S. G. Zlotina, O. A. Baninab, D. V. Sudarikovb, A. A. Nigmatova, L. L. Frolovab, A. V. Kutchinb
a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
b Institute of Chemistry, Komi Science Center, Ural Branch of the Russian Academy of Sciences, Syktyvkar, Russian Federation
Аннотация:
Asymmetric aldol reactions of isatin and 4,6-dibromoisatin with acetone are efficiently catalyzed by b-amino alcohols derived from a-pinene and 3-carene. The target compounds can be isolated by crystallization from toluene, which
eliminates the need for using chromatography and makes the asymmetric
synthesis of (R)-convolutamydine A (up to 94% ee and yield 75%) simple and convenient.
Ключевые слова:
aldol reaction, b-amino alcohols, 3-carene, α-pinene, isatin, 4,6-dibromoisatin, convolutamydine A.
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc1129
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