Investigation of the structure of non-crystalline systems and the structure of proteins in solution by small-angle scattering, computer-aided analysis of non-separated mixture spectra

Surname, first name, other names: Volkov Vladimir Vladimirovich Date and Place of Birth: July 25, 1953, Moscow, Russia. Citizenship: Russia Position: A.V. Shubnikov Institute of Crystallography, Federal Research Center for Crystallography and Photonics, Russian Academy of Sciences Address: Leninsky Prospekt, 59, 119333 Moscow, Russia. Address for correspondence: V.V. Volkov, V.A. Shubnikov Institute of Crystallography, Russian Academy of Sciences, Laboratory of Small-Angle Scattering. 119333, 59 Leninsky Prospekt, Moscow, Russia. Fax: (007-499) 135 10 11 E-mail: vvo@ns.crys.ras.ru, volkicras@mail.ru Education: 1975 Moscow State University, Chemistry Department, Moscow, Russia. Diploma subject: "Study of the reaction of Mo with nioxime by the EPR method". 1990 Candidate of Chemical Sciences. D. thesis topic: "The use of additional information in the decomposition of the spectra of mixtures into spectra of components". 2014 г. Ph.D. in Chemistry. D. thesis topic: "Spectroscopy and small-angle scattering in inverse problems of research of multicomponent systems". Career/work: 1975-1983: Engineer, researcher, Institute of Industrial Wastewater, Moscow, USSR. 1983-2021: Engineer, researcher, senior researcher, head of laboratory of X-ray small-angle scattering, leading researcher. A.V. Shubnikov Institute of Crystallography, Russian Academy of Sciences. 2022: Senior researcher at the Federal Research Center for Crystallography and Photonics of the Russian Academy of Sciences. Specialization: Main area: Research on the structure of disordered and partially ordered nanosystems, numerical methods in low angle scattering and numerical methods in analytical chemistry. Development of programs for processing and interpretation of small angle scattering data, structure determination of biopolymers in solution and nanoscale complex systems. Other fields: Electron spin resonance in crystals, numerical methods for nonlinear minimization and linear algebra, software development for solving inverse problems in physics. Professional societies: Russian Biochemical Society, IUCR. Number of papers in peer-reviewed journals: 160 Number of communications at scientific meetings: 137 Author's diplomas and patents 3 Selected publications: 1. Svergun D.I., Volkov V.V., Kozin M.B. & Stuhrmann H.B. New Developments in Direct Shape Determination from Small-Angle Scattering. 2. Uniqueness. // Acta Cryst, 1996, A52, pp.419-426. DOI: 10.1107/S0108767396000177 2. V.V.Volkov. Separation of Additive Mixture Spectra by a Self-Modeling Method. // Applied Spectroscopy, 1996, 50/3, pp. 320-326. DOI: 10.1366/0003702963906357 3. Svergun, D. I., Burkhardt, N., Skov Pedersen, J., Koch, M. H. J., Volkov, V. V., Kozin, M. B., Meerwink, W., Stuhrmann, H. B., Diedrich, G. & Nierhaus, K. H. Solution Scattering Structural Analysis of the 70S Escherichia coli Ribosome by Contrast Variation: I. Invariants and Validation of Electron Microscopy Models. // J. Mol. Biol., 1997, 271, pp.588-601. DOI: 10.1006/jmbi.1997.1190; II. Structure modelling. // J. Mol. Biol., 271, pp.602-618. DOI: 10.1006/jmbi.1997.1191 4. Volkov V.V., Lapuk V.A., Kayushina R.L., Shtykova E.V., Varlamova E.Yu., Malfois M. and Svergun D.I. Low-resolution structure of immunoglobulins IgG1, IgM and rheumatoid factor IgM-RF from solution X-ray scattering data. // J. Appl. Cryst., 2003, 36, pp.503-508. DOI: 10.1107/S0021889803005156 5. Volkov V.V. and Svergun D.I. Uniqueness of ab initio shape determination in small-angle scattering. // J. Appl. Cryst., 2003, 36, pp.860-864. DOI: 10.1107/S0021889803000268 6. Konarev P.V., Petoukhov M.V., Volkov V.V., Svergun, D.I. ATSAS 2.1, a program package for small-angle scattering data analysis. // J. Appl. Crystallogr. 2006, 39, pp.277-286. DOI: 10.1107/S0021889806004699 7. Volkov V.V., Lapuk V.A., Toropova A.I., et al. A comparative study of immunoglobulin IgM and rheumatoid factor IgMRF in solution b

1. V. V. Volkov, “VOLDIS: A Direct Search for the Size Distribution of Nanoparticles from Small-Angle Scattering Data and Stability of the Solution”, Crystals, 12 (2022), 1-15
2. P. V. Konarev, M. A. Graewert, Cy M. Jeffries, M. Fukuda, T. A. Cheremnykh, V. V. Volkov, D. I. Svergun, “EFAMIX, a tool to decompose inline chromatography SAXS data from partially overlapping components”, DOI:10.1002/pro.4237, Protein Science, 31 (2022), 269-282
3. E. M. Chistyakov, S. N. Filatov, E. A. Sulyanova, V. V. Volkov, “Determination of the Degree of Crystallinity of poly(2–methyl–2–oxazoline)”, DOI: 10.3390/polym13244356, Polymers, 13 (2021), 1-9
4. V. V. Volkov, “On the Tactics of Ab Initio Search for the Shape of Protein Particles from Small–Angle X–Ray Scattering Data”, DOI:10.1134/S1063774521050230, Crystallography Reports, 66:5 (2021), 819-827
5. V. V. Volkov, “Separation of Additive Mixture Spectra by a Self–Modeling Method”, DOI:10.1366/0003702963906357, Applied Spectroscopy, 50:3 (1996), 320–326

• Institute of Cristallography Russian Academy of Sciences, Moscow
• A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Moscow