Sibirskii Zhurnal Vychislitel'noi Matematiki
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Sibirskii Zhurnal Vychislitel'noi Matematiki, 2019, Volume 22, Number 4, Pages 399–414
DOI: https://doi.org/10.15372/SJNM20190402 (Mi sjvm722) 		 
This article is cited in 4 scientific papers (total in 4 papers)

A numerical method for predicting hemodynamic effects in vascular prostheses

V. G. Borisovab, Yu. N. Zakharovab, Yu. I. Shokina, E. A. Ovcharenkoc, K. Y. Klyshnikovc, I. N. Sizovac, A. V. Batranind, Y. A. Kudryavtsevac, P. S. Onishchenkoac

a Institute of Computational Technologies, Siberian Branch, Russian Academy of Sciences, pr. Akad. Lavrent’eva 6, Novosibirsk, 603090 Russia
b Kemerovo State University, ul. Krasnaya 6, Kemerovo, 650000 Russia
c Kemerovo Cardiology Center, Sosnovyi blv. 6, Kemerovo, 650002 Russia
d Tomsk Polytechnic University, pr. Lenina 30, Tomsk, 634050 Russia
Full-text PDF (8289 kB) Citations (4)
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DOI: https://doi.org/10.15372/SJNM20190402
Abstract: The three-dimensional unsteady-state periodic flow of blood in xenogenic vascular bioprostheses is simulated using computational fluid dynamics methods. The geometry of the computational domain is based on microtomographic scanning of bioprostheses. To set a variable pressure gradient causing a non-stationary flow in the prostheses, personal-specific data of the Doppler-echography of the blood flow of a particular patient are used. A comparative analysis of the velocity fields in the flow areas corresponding to three real samples of bioprostheses with multiple stenoses is carried out. In the zones of stenosis and outside of them, the distribution of the near-wall shear stress, which influences the risk factors for thrombosis in the prostheses, is analyzed. An algorithm for predicting the hemodynamic effects arising in vascular bioprostheses, based on the numerical modeling of a blood flow in them, is proposed.
Key words: computer modeling, blood flow, bioprostheses, wall shear stress.
Funding agency Grant number
Siberian Branch of Russian Academy of Sciences 26
0546-2015-0011
This work was supported by the Complex Program of Basic Research of the Siberian Branch of the Russian Academy of Sciences (project no. 26 “Biodegradable small-diameter vascular graft modified by functionally active peptides”) and by the Complex Program of Basic Research of the Siberian Branch of the Russian Academy of Sciences within the framework of the fundamental topic of the Kemerovo Cardiology Center no. 0546-2015-0011 “Pathogenetic justification of the development of implants for cardio-vascular surgery on the basis of biocompatible materials with implementation of the patientoriented approach involving mathematical modeling, tissue engineering, and genome predictors.”
Received: 26.10.2018
Revised: 19.02.2019
Accepted: 25.07.2019
English version:
Numerical Analysis and Applications, 2019, Volume 12, Issue 4, Pages 326–337
DOI: https://doi.org/10.1134/S1995423919040025
Bibliographic databases:
Document Type: Article
UDC: 519.6, 51-76
Language: Russian
Citation: V. G. Borisov, Yu. N. Zakharov, Yu. I. Shokin, E. A. Ovcharenko, K. Y. Klyshnikov, I. N. Sizova, A. V. Batranin, Y. A. Kudryavtseva, P. S. Onishchenko, “A numerical method for predicting hemodynamic effects in vascular prostheses”, Sib. Zh. Vychisl. Mat., 22:4 (2019), 399–414; Num. Anal. Appl., 12:4 (2019), 326–337
Citation in format AMSBIB
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\jour Sib. Zh. Vychisl. Mat.
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\issue 4
\pages 399--414
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\crossref{https://doi.org/10.15372/SJNM20190402}
\transl
\jour Num. Anal. Appl.
\yr 2019
\vol 12
\issue 4
\pages 326--337
\crossref{https://doi.org/10.1134/S1995423919040025}
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