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Russian Chemical Reviews, 2018, Volume 87, Issue 11, Pages 1111–1138
DOI: https://doi.org/10.1070/RCR4832
(Mi rcr4228)
 

This article is cited in 21 scientific papers (total in 21 papers)

Benzimidazole nucleosides: antiviral and antitumour activities and methods of synthesis

M. I. Kharitonova, I. D. Konstantinova, A. I. Miroshnikov

M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow
English full-text Citations (21)
Abstract: The review systematically covers experimental data on the synthesis of modified benzimidazole nucleosides and evaluation of their biological activity published mainly over the last two decades. Various synthetic approaches to benzimidazole nucleosides, from multistep chemical processes to up-to-date biotechnology-based methods, are considered. A historical background of the development and structural improvement of various benzimidazole nucleosides is given and the structure–activity relationships for the synthesized compounds are addressed. Data on the antiviral and antitumour activities of these derivatives are presented and the cellular targets of benzimidazole nucleosides are discussed.
The bibliography includes 160 references.
Received: 25.04.2018
Russian version:
Uspekhi Khimii, 2018, Volume 87, Issue 11, Pages 1111–1138
DOI: https://doi.org/10.1070/RCR4832
Bibliographic databases:
Document Type: Article
Language: English
Original paper language: Russian
Citation: M. I. Kharitonova, I. D. Konstantinova, A. I. Miroshnikov, “Benzimidazole nucleosides: antiviral and antitumour activities and methods of synthesis”, Usp. Khim., 87:11 (2018), 1111–1138; Russian Chem. Reviews, 87:11 (2018), 1111–1138
Citation in format AMSBIB
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\by M.~I.~Kharitonova, I.~D.~Konstantinova, A.~I.~Miroshnikov
\paper Benzimidazole nucleosides: antiviral and antitumour activities and methods of synthesis
\jour Usp. Khim.
\yr 2018
\vol 87
\issue 11
\pages 1111--1138
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\crossref{https://doi.org/10.1070/RCR4832}
\adsnasa{https://adsabs.harvard.edu/cgi-bin/bib_query?2018RuCRv..87.1111K}
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\jour Russian Chem. Reviews
\yr 2018
\vol 87
\issue 11
\pages 1111--1138
\crossref{https://doi.org/10.1070/RCR4832}
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\scopus{https://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85056127408}
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  • https://www.mathnet.ru/eng/rcr4228
  • https://doi.org/10.1070/RCR4832
  • https://www.mathnet.ru/eng/rcr/v87/i11/p1111
  • This publication is cited in the following 21 articles:
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