Chemistry of 1-aza-1,3-enynes: achievements and key trends of development

The data on the chemistry of 1-aza-1,3-enynes published in the past 15 years have been summarized and systematized. Achievements in the synthesis of these compounds, as well as their transformations into various acyclic and heterocyclic nitrogenous products, have been surveyed. Particular attention has focused on the addition reactions at the azomethine and/or carbon–carbon triple bonds. Practical applications of the products of these transformations, first of all, in synthesis of complex natural and biologically active compounds, are discussed. The bibliography includes 161 references.