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This article is cited in 34 scientific papers (total in 34 papers)
Development of approaches to a third-generation carbohydrate-conjugate vaccine against Streptococcus pneumoniae: the search for optimal oligosaccharide ligands
M. L. Geninga, E. A. Kurbatovab, Yu. E. Tsvetkova, N. E. Nifantieva a N.D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences
b I.I. Mechnikov Research Institute for Vaccines and Sera
Abstract:
The review addresses the application of synthetic oligosaccharides related to fragments of capsular polysaccharides from different serotypes of the bacterium Streptococcus pneumoniae for the design of third-generation pneumococcal conjugate vaccines. Special focus is given to characteristic features of the chemical structures of oligosaccharides required for the induction of the protective immune response when using synthetic glycoconjugate vaccines based on oligosaccharide ligands and carrier proteins.
The bibliography includes 101 references.
Received: 01.06.2015
Citation:
M. L. Gening, E. A. Kurbatova, Yu. E. Tsvetkov, N. E. Nifantiev, “Development of approaches to a third-generation carbohydrate-conjugate vaccine against Streptococcus pneumoniae: the search for optimal oligosaccharide ligands”, Usp. Khim., 84:11 (2015), 1100–1113; Russian Chem. Reviews, 84:11 (2015), 1100–1113
Linking options:
https://www.mathnet.ru/eng/rcr4076https://doi.org/10.1070/RCR4574 https://www.mathnet.ru/eng/rcr/v84/i11/p1100
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