Photothermal effect of infrared (808 nm) laser radiation and gold nanoparticles in different modifications on s. aureus

A comparative study of the effect of infrared laser radiation (808 nm) of different power density on Staphylococcus aureus 209 P, incubated in solutions of gold nanocubes, nanorods, and on the surface of glasses with coating made of gold nanodisks is performed. Radiation with power density of 60 mW/сm$^2$ combined with nanocubes caused the death of 50% of the population after 30 min of exposure, and combined with nanorods caused the death of 56% of the population. An increase of temperature of suspensions after exposure was noticed not more than by 5–6$^{\circ}$С. Radiation with power density of 400 mW/сm$^2$ caused a pronounced inhibition of vitality of bacterial cells by 81% after 30 min. Incubation of suspensions of microorganisms on the surface of glasses, which contain gold nanodisks, in the course of exposure (808 nm, 400 mW/сm$^2$) caused 99% death of bacterial cells.