Abstract:
A cobalt-catalyzed redox-neutral [4 + 2] annulation of oximes and alkynes in deep eutectic solvents comprising quaternary ammonium compounds and hydrogen bond donors has been developed, the best system being Me3N+CH2CO2- / HOCH(CF3)2. No external oxidizing reagent was required, and only water was generated as the secondary product. The catalytic system can be reused in three consecutive cycles.
Citation:
L. Wang, L. Zhang, L. Gong, “Cobalt(III)-catalyzed synthesis of isoquinolines from oximes and alkynes in deep eutectic solvents”, Mendeleev Commun., 33:2 (2023), 243–245
Linking options:
https://www.mathnet.ru/eng/mendc363
https://www.mathnet.ru/eng/mendc/v33/i2/p243
This publication is cited in the following 4 articles:
Sushobhan Mukhopadhyay, Sampa Gupta, Nicholas Guadagnoli, Christopher R. McCurdy, “Advances in the Synthesis of Isoquinolines Using an Alkyne Coupling Partner via Transition‐Metal‐Catalyzed C─H Activation”, ChemistrySelect, 10:2 (2025)
L. Ye, Zh. Zhao, E.-x. Lei, L. Wang, “One-pot two-step synthesis of γ-keto sulfones in deep eutectic solvent”, Mendeleev Commun., 34:5 (2024), 709–710
Darun Yang, Hongyan Xu, Xuejun Zhang, Yuntao Hu, Decai Huang, Huaiqing Zhao, “Ru-catalyzed C–H activation/cyclization of oximes with sulfoxonium ylides to access isoquinolines”, Org. Biomol. Chem., 21:33 (2023), 6750
Vipin K. Maikhuri, Manish Rawat, Diwan S. Rawat, “Recent Advances in the 3 d‐Transition‐Metal‐Catalyzed Synthesis of Isoquinolines and its Derivatives”, Adv Synth Catal, 365:24 (2023), 4458
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