Abstract:
The first synthesis of a family of betulin-based triterpene–polyamine conjugates, which are structurally related to the potential antibiotic squalamine, is demonstrated.
Citation:
G. V. Giniyatullina, O. B. Flekhter, G. A. Tolstikov, “Synthesis of squalamine analogues on the basis of lupane triterpenoids”, Mendeleev Commun., 19:1 (2009), 32–33
Linking options:
https://www.mathnet.ru/eng/mendc3108
https://www.mathnet.ru/eng/mendc/v19/i1/p32
This publication is cited in the following 6 articles:
Oxana Kazakova, Irina Smirnova, Ha Thi Thu Nguyen, Niels V. Heise, Sophie Hoenke, Immo Serbian, René Csuk, “α-Glucosidase and cholinesterase inhibiting potential of a series of semisynthetic nitrogen triterpenic derivatives”, Med Chem Res, 32:3 (2023), 485
Oxana Kazakova, Gulnara Giniyatullina, Denis Babkov, Zdenek Wimmer, “From Marine Metabolites to the Drugs of the Future: Squalamine, Trodusquemine, Their Steroid and Triterpene Analogues”, IJMS, 23:3 (2022), 1075
G. V. Giniyatullina, “Synthesis and Antitumor Activity of O- and N-Propylamino-Derivatives of Betulin”, Chem Nat Compd, 58:4 (2022), 684
Anna Yu. Spivak, Rezeda R. Khalitova, Darya A. Nedopekina, Rinat R. Gubaidullin, “Antimicrobial properties of amine- and guanidine-functionalized derivatives of betulinic, ursolic and oleanolic acids: Synthesis and structure/activity evaluation”, Steroids, 154 (2020), 108530
Oxana B. Kazakova, Gul'nara V. Giniyatullina, Akhat G. Mustafin, Denis A. Babkov, Elena V. Sokolova, Alexander A. Spasov, “Evaluation of Cytotoxicity and α-Glucosidase Inhibitory Activity of Amide and Polyamino-Derivatives of Lupane Triterpenoids”, Molecules, 25:20 (2020), 4833
Anna Spivak, Rezeda Khalitova, Darya Nedopekina, Lilya Dzhemileva, Milyausha Yunusbaeva, Victor Odinokov, Vladimir D'yakonov, Usein Dzhemilev, “Synthesis and Evaluation of Anticancer Activities of Novel C-28 Guanidine-Functionalized Triterpene Acid Derivatives”, Molecules, 23:11 (2018), 3000
Contact us: