Abstract:
The derivatives of aliphatic tripeptides containing l-ornithine, l-lysine and diesters of l-glutamic acid were synthesized, the physico- chemical properties of dispersions based on them were examined and the dependence of transfection efficiency on the amphiphile:DNA ratio and the structure of the peptides was evaluated.
Citation:
O. O. Koloskova, U. A. Budanova, A. M. Sumina, G. A. Sarychev, Yu. L. Sebyakin, “Ornithine and lysine based lipotripeptides: synthesis and comparison of transfection efficiency”, Mendeleev Commun., 24:5 (2014), 262–263
Linking options:
https://www.mathnet.ru/eng/mendc2545
https://www.mathnet.ru/eng/mendc/v24/i5/p262
This publication is cited in the following 9 articles:
M. R. Ibatullina, E. P. Zhil´tsova, S. S. Lukashenko, V. I. Kovalenko, I. I. Vandyukova, M. P. Kutyreva, L. Ya. Zakharova, “Mixed micellar systems of metal complexes of alkylated N-methyl-d-glucamines with hexadecyltrimethylammonium bromide”, Russ Chem Bull, 68:2 (2019), 424
O.O. Koloskova, A.M. Gileva, M.G. Drozdova, M.V. Grechihina, N.E. Suzina, U.A. Budanova, Yu.L. Sebyakin, D.A. Kudlay, I.P. Shilovskiy, A.M. Sapozhnikov, E.I. Kovalenko, E.A. Markvicheva, M.R. Khaitov, “Effect of lipopeptide structure on gene delivery system properties: Evaluation in 2D and 3D in vitro models”, Colloids and Surfaces B: Biointerfaces, 167 (2018), 328
V. V. Marusova, R. I. Zagitova, U. A. Budanova, Yu. L. Sebyakin, “Multifunctional Lipoamino Acid Derivatives with Potential Biological Activity”, Moscow Univ. Chem. Bull., 73:2 (2018), 74
A.S. Nosova, O.O. Koloskova, I.P. Shilovskiy, Yu.L. Sebyakin, M.R. Khaitov, “Lactose-based glycoconjugates with variable spacers for design of liver-targeted liposomes”, BIOMED KHIM, 63:5 (2017), 467
Antara Dasgupta, “Exploring architectures at the nanoscale: the interplay between hydrophobic twin lipid chains and head groups of designer peptide amphiphiles in the self-assembly process and application”, Soft Matter, 12:19 (2016), 4352
V. E. Kuznetsova, M. A. Spitsyn, V. E. Shershov, T. O. Guseinov, E. E. Fesenko, S. A. lapa, A. Yu. Ikonnikova, M. A. Avdonina, T. V. Nasedkina, A. S. Zasedatelev, A. V. Chudinov, “Novel fluorescently labeled nucleotides: synthesis, spectral properties and application in polymerase chain reaction”, Mendeleev Commun., 26:2 (2016), 95–98
U. A. Budanova, I. S. Shchelik, O. O. Koloskova, Yu. L. Sebyakin, “Multivalent glycoconjugate as the vector of target delivery of bioactive compounds”, Mendeleev Commun., 26:3 (2016), 205–206
U. A. Budanova, V. V. Marusova, Yu. L. Sebyakin, “Properties and transfection activity of cationic dimeric amphiphiles based on amino acids”, Mendeleev Commun., 26:2 (2016), 101–102
D. R. Gabdrakhmanov, F. G. Valeeva, V. V. Syakaev, S. S. Lukashenko, S. V. Zakharov, D. A. Kuryashov, N. Yu. Bashkirtseva, L. Ya. Zakharova, Sh. K. Latypov, O. G. Sinyashin, “Novel supramolecular system based on a cationic amphiphile bearing glucamine fragment: structural behavior and hydrophobic probe binding”, Mendeleev Commun., 25:3 (2015), 174–176
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