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Mendeleev Communications, 2017, Volume 27, Issue 6, Pages 628–630
DOI: https://doi.org/10.1016/j.mencom.2017.11.031 (Mi mendc2083) 		 
This article is cited in 3 scientific papers (total in 3 papers)

Communications

A novel diastereoselective α-functionalization of proline with benzaldehydes: synthesis of α-(α-hydroxybenzyl)prolines

A. V. Pavlushin, V. S. Moshkin, V. Ya. Sosnovskikh

Department of Chemistry, Ural Federal University, Ekaterinburg, Russian Federation
Full-text PDF (221 kB) Citations (3)
DOI: https://doi.org/10.1016/j.mencom.2017.11.031
Abstract: 2-Oxapyrrolizidines formed in reactions of methyl prolinate with two molecules of aromatic aldehyde upon gradual hydrolysis give α-(α-hydroxybenzyl)prolines. The products are preferentially formed as one diastereomer (91–100%) in overall yield 33–50% (five stages starting from proline).
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (359.9 Kb)


Citation: A. V. Pavlushin, V. S. Moshkin, V. Ya. Sosnovskikh, “A novel diastereoselective α-functionalization of proline with benzaldehydes: synthesis of α-(α-hydroxybenzyl)prolines”, Mendeleev Commun., 27:6 (2017), 628–630
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  • https://www.mathnet.ru/eng/mendc/v27/i6/p628
    • This publication is cited in the following 3 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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