O. O. Koloskova, A. S. Nosova, I. S. Shchelik, I. P. Shilovskiy, Yu. L. Sebyakin, M. R. Khaitov, “Liver-targeted delivery of nucleic acid by liposomes modified with a glycoconjugate”, Mendeleev Commun., 27:6 (2017), 626

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Mendeleev Communications, 2017, Volume 27, Issue 6, Pages 626–627
DOI: https://doi.org/10.1016/j.mencom.2017.11.030 (Mi mendc2082)

This article is cited in 8 scientific papers (total in 8 papers)

Communications

Liver-targeted delivery of nucleic acid by liposomes modified with a glycoconjugate

O. O. Koloskova^ab, A. S. Nosova^ab, I. S. Shchelik^b, I. P. Shilovskiy^a, Yu. L. Sebyakin^b, M. R. Khaitov^a

^a State Research Center 'Institute of Immunology', Federal Medico-Biological Agency, Moscow, Russian Federation
^b M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation

Full-text PDF (262 kB) Citations (8)

DOI: https://doi.org/10.1016/j.mencom.2017.11.030

Graphic abstract: Liver-targeted delivery of nucleic acid by liposomes modified with a glycoconjugate

Abstract: A drug delivery system based on liposomes has been modified by targeted vectors based on a glycoconjugate, and the vector structure has been optimized. The glycoconjugate in liposomes almost fourfold increases the transfection efficiency of the delivery system in specific human liver cell line (HepG2) in comparison with that of unmodified lipopeptide-based liposomes.

Document Type: Article

Language: English

Citation: O. O. Koloskova, A. S. Nosova, I. S. Shchelik, I. P. Shilovskiy, Yu. L. Sebyakin, M. R. Khaitov, “Liver-targeted delivery of nucleic acid by liposomes modified with a glycoconjugate”, Mendeleev Commun., 27:6 (2017), 626–627

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https://www.mathnet.ru/eng/mendc2082

https://www.mathnet.ru/eng/mendc/v27/i6/p626

This publication is cited in the following 8 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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