Abstract:
Direct esterification of betulin with coumarin-3-carboxylic or 3,4,5-trimethoxybenzoic acid led to betulin-28-esters and betulin-3,28-diesters. The betulin-3-esters were synthesized through 28-O-protection, esterification and deprotection steps using betulin as a starting material.
Document Type:
Article
Language: English
Citation:
G.-Ya. Wang, L. Jin, F.-Yu. Piao, R.-B. Han, “Betulin esters with coumarin-3-carboxylic and 3,4,5-trimethoxybenzoic acids”, Mendeleev Commun., 27:1 (2017), 93–94
Linking options:
https://www.mathnet.ru/eng/mendc1907
https://www.mathnet.ru/eng/mendc/v27/i1/p93
This publication is cited in the following 3 articles:
A. S. SIMAGIN, K. V. SHIRSHIN, D. V. OREKHOV, D. M. KAMORIN, O. A. KAZANTSEV, S. A. OZHOGIN, “(Meth)acrylic esters of betulin and their copolymers with hydrophilic methacrylic esters and amides”, Plastičeskie massy, 1:1-2 (2022), 20
Monika Kadela-Tomanek, Maria Jastrzȩbska, Elwira Chrobak, Ewa Bȩbenek, Stanisław Boryczka, “Chromatographic and Computational Screening of Lipophilicity and Pharmacokinetics of Newly Synthesized Betulin-1,4-quinone Hybrids”, Processes, 9:2 (2021), 376
Monika Kadela-Tomanek, Ewa Bȩbenek, Elwira Chrobak, Krzysztof Marciniec, Małgorzata Latocha, Dariusz Kuśmierz, Maria Jastrzȩbska, Stanisław Boryczka, “Betulin-1,4-quinone hybrids: Synthesis, anticancer activity and molecular docking study with NQO1 enzyme”, European Journal of Medicinal Chemistry, 177 (2019), 302
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