E. V. Verbitskiy, S. A. Baskakova, N. A. Gerasimova, N. P. Evstigneeva, N. V. Zil'berberg, N. V. Kungurov, M. A. Kravchenko, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin, “New 5-arylamino-4-(5-nitrofuran-2-yl)pyrimidines as promising antibacterial agents”, Mendeleev Commun., 28:4 (2018), 393

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Mendeleev Communications, 2018, Volume 28, Issue 4, Pages 393–395
DOI: https://doi.org/10.1016/j.mencom.2018.07.017 (Mi mendc1777)

This article is cited in 13 scientific papers (total in 13 papers)

Communications

New 5-arylamino-4-(5-nitrofuran-2-yl)pyrimidines as promising antibacterial agents

E. V. Verbitskiy^ab, S. A. Baskakova^a, N. A. Gerasimova^c, N. P. Evstigneeva^c, N. V. Zil'berberg^c, N. V. Kungurov^c, M. A. Kravchenko^d, G. L. Rusinov^ab, O. N. Chupakhin^ab, V. N. Charushin^ab

^a I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^b Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
^c Ural Research Institute for Dermatology, Venereology and Immunopathology, Ekaterinburg, Russian Federation
^d Ural Research Institute for Phthisiopulmonology, Ekaterinburg, Russian Federation

Full-text PDF (652 kB) Citations (13)

DOI: https://doi.org/10.1016/j.mencom.2018.07.017

Graphic abstract: New 5-arylamino-4-(5-nitrofuran-2-yl)pyrimidines as promising antibacterial agents

Abstract: A facile synthetic approach to 5-arylamino-4-(5-nitrofuran- 2-yl)pyrimidines by the Buchwald–Hartwig cross-coupling with various anilines has been developed. All synthesized compounds demonstrated a significant level of in vitro antibacterial activity against Neisseria gonorrhoeae, Streptococcus pyogene and Staphylococcus aureus, including their drug-resistant strains, which is much higher than that of the commercial drug Spectinomycin.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(720.2 Kb)

Citation: E. V. Verbitskiy, S. A. Baskakova, N. A. Gerasimova, N. P. Evstigneeva, N. V. Zil'berberg, N. V. Kungurov, M. A. Kravchenko, G. L. Rusinov, O. N. Chupakhin, V. N. Charushin, “New 5-arylamino-4-(5-nitrofuran-2-yl)pyrimidines as promising antibacterial agents”, Mendeleev Commun., 28:4 (2018), 393–395

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https://www.mathnet.ru/eng/mendc/v28/i4/p393

This publication is cited in the following 13 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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