Abstract:
Three novel uracil-based morpholine nucleosides each containing three different orthogonally reactive functional groups, namely, amino, carboxy and acetylene ones, were synthesized. The obtained monomers are intended for the synthesis of labeled nucleotide, nucleic acid or peptide mimics.
Citation:
T. V. Abramova, L. S. Koroleva, V. N. Silnikov, “New orthogonally trifunctionalized morpholine nucleosides”, Mendeleev Commun., 29:2 (2019), 169–171
Linking options:
https://www.mathnet.ru/eng/mendc1459
https://www.mathnet.ru/eng/mendc/v29/i2/p169
This publication is cited in the following 2 articles:
Irina Chernyshova, Inna Vasil'eva, Nina Moor, Nikita Ivanisenko, Mikhail Kutuzov, Tatyana Abramova, Alexandra Zakharenko, Olga Lavrik, “Aminomethylmorpholino Nucleosides as Novel Inhibitors of PARP1 and PARP2: Experimental and Molecular Modeling Analyses of Their Selectivity and Mechanism of Action”, IJMS, 25:23 (2024), 12526
Nicola Schiaroli, Camilla Loro, Sara Colombo, Gianluigi Broggini, Marta Papis, Francesca Foschi, “Morpholine Scaffolds' Preparation for Foldamers' Design and Construction”, Asian J Org Chem, 13:1 (2024)
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