N. G. Morozova, E. V. Shmendel, G. A. Timofeev, I. V. Ivanov, T. S. Kubasova, N. V. Plyavnik, A. A. Markova, M. A. Maslov, A. A. Shtil, “New design of cationic alkyl glycoglycerolipids toxic to tumor cells”, Mendeleev Commun., 29:2 (2019), 166

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Mendeleev Communications, 2019, Volume 29, Issue 2, Pages 166–168
DOI: https://doi.org/10.1016/j.mencom.2019.03.016 (Mi mendc1458)

This article is cited in 4 scientific papers (total in 4 papers)

Communications

New design of cationic alkyl glycoglycerolipids toxic to tumor cells

N. G. Morozova^a, E. V. Shmendel^a, G. A. Timofeev^a, I. V. Ivanov^a, T. S. Kubasova^a, N. V. Plyavnik^a, A. A. Markova^bc, M. A. Maslov^a, A. A. Shtil^b

^a M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation
^b N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation
^c A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation

Full-text PDF (282 kB) Citations (4)

DOI: https://doi.org/10.1016/j.mencom.2019.03.016

Graphic abstract: New design of cationic alkyl glycoglycerolipids toxic to tumor cells

Abstract: New glycosylated alkyl glycerolipids bearing a cationic group at the C⁶ position of sugar moiety have been synthesized and tested as potential anticancer drugs. The compounds demonstrated cytotoxicity and selectivity against tumor cells at low micromolar concentration.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(502.4 Kb)

Citation: N. G. Morozova, E. V. Shmendel, G. A. Timofeev, I. V. Ivanov, T. S. Kubasova, N. V. Plyavnik, A. A. Markova, M. A. Maslov, A. A. Shtil, “New design of cationic alkyl glycoglycerolipids toxic to tumor cells”, Mendeleev Commun., 29:2 (2019), 166–168

Linking options:

https://www.mathnet.ru/eng/mendc1458

https://www.mathnet.ru/eng/mendc/v29/i2/p166

This publication is cited in the following 4 articles:

Arseny D. Moralev, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Andrey V. Markov, “Soloxolone N-3-(Dimethylamino)propylamide Restores Drug Sensitivity of Tumor Cells with Multidrug-Resistant Phenotype via Inhibition of P-Glycoprotein Efflux Function”, Molecules, 29:20 (2024), 4939
Marco Antônio G B Gomes, Alicia Bauduin, Chloé Le Roux, Romain Fouinneteau, Wilfried Berthe, Mathieu Berchel, Hélène Couthon, Paul-Alain Jaffrès, “Synthesis of ether lipids: natural compounds and analogues”, Beilstein J. Org. Chem., 19 (2023), 1299
E. A. Varlamova, A. K. Isagulieva, N. G. Morozova, E. V. Shmendel, M. A. Maslov, A. A. Shtil, “Non-Phosphorus Lipids As New Antitumor Drug Prototypes”, Russ J Bioorg Chem, 47:5 (2021), 965
A. I. Nichugovskiy, A. A. Khrulev, K. A. Perevoshchikova, D. A. Cheshkov, N. G. Morozova, M. A. Maslov, “Synthesis of Isonitrile Derivatives of Diglycerides and Carbohydrates as Intermediates for Multicomponent Ugi Reaction”, Russ J Bioorg Chem, 47:4 (2021), 929

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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