Abstract:
The reaction of 2-alkoxy- and 2-alkylthio-3-(het)arylpropenals with tosylmethyl isocyanide affords oxazoles bearing the corresponding 5-positioned 1-alkylchalcogenyl-2-(het)arylvinyl groups.
Citation:
N. V. Vchislo, V. G. Fedoseeva, V. V. Novokshonov, L. I. Larina, I. B. Rosentsveig, E. A. Verochkina, “Synthesis of new alkoxy/alkylthiovinylated oxazoles using tosylmethyl isocyanide”, Mendeleev Commun., 30:3 (2020), 350–351
Linking options:
https://www.mathnet.ru/eng/mendc1194
https://www.mathnet.ru/eng/mendc/v30/i3/p350
This publication is cited in the following 7 articles:
Pravin J. Wanjari, Kriti Mehta, Marudhvathi Kudumula, Rohit Sharma, Prasad V. Bharatam, “Recent developments in the metal-free synthesis of oxazoles”, Tetrahedron, 169 (2025), 134363
Umang P. Patel, Parth S. Unjiya, Vaishali K. Rathod, Ranjitsinh C. Dabhi, Vidhi A. Trivedi, Manish K. Shah, “2‐(3‐Iodo‐4‐Methylphenyl)‐4‐(aryl)oxazol‐5(4H)‐one Analogs: Synthesis, Anticancer Screening, SAR, in silico Molecular Docking, and ADMET Studies”, ChemistrySelect, 10:6 (2025)
Patrick Wagner, Mihaela Gulea, Nicolas Girard, “Hydroformylation of Alkynyl Sulfides: A Stereo‐ and Regioselective Route to α‐Sulfenyl Acroleins”, Adv Synth Catal, 366:6 (2024), 1298
Nadezhda V. Vchislo, Victoria G. Fedoseeva, Ekaterina A. Verochkina, “The Reactions of p-Tosylmethyl Isocyanide with Aldehydes in the Synthesis
of Heterocyclic Compounds: A Review”, MROC, 20:4 (2023), 372
Nadezhda V. Vchislo, Ekaterina A. Verochkina, Victoria G. Fedoseeva, “Synthesis of alkenyl- and alkynyloxazoles and –oxazolines using tosylmethyl isocyanide as a key building block (microreview)”, Chem Heterocycl Comp, 59:8 (2023), 537
Yuting Wan, Jieqing Wu, Hongfei Ma, Hongjun Zhu, Patrick J. Walsh, Yufeng Li, “Copper(i)-catalyzed tandem synthesis of 4,5-functionalized oxazoles from isocyanoacetate and aldehydes”, New J. Chem., 46:35 (2022), 16840
Ekaterina A. Verochkina, Nadezhda Victorovna Vchislo, Igor B. Rozentsveig, “α-Functionally Substituted α,β-Unsaturated Aldehydes as Fine Chemicals Reagents: Synthesis and Application”, Molecules, 26:14 (2021), 4297
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