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Эта публикация цитируется в 3 научных статьях (всего в 3 статьях)
CHEMISTRY AND MATERIAL SCIENCE
Pvp-stabilized tungsten oxide nanoparticles (WO$_3$) nanoparticles cause hemolysis of human erythrocytes in a dose-dependent manner
A. L. Popova, I. V. Savintsevaa, N. R. Popovaa, T. O. Shekunovabc, O. S. Ivanovac, A. B. Shcherbakovd, D. A. Kozlovb, V. K. Ivanovbc a Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences,
Pushchino, Moscow region, 142290, Russia
b Lomonosov Moscow State University, Moscow, 119991, Russia
c Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russia
d Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine,
Kyiv, D0368, Ukraine
Аннотация:
Tungsten oxide nanoparticles (WO$_3$ NPs) are increasingly being considered as a promising material for biomedical applications. However, toxicological information on their effect on red blood cells (RBCs) remains very scarce. In this study, we examined the toxicity of PVP-stabilized tungsten oxide nanoparticles against human RBCs. Optical microscopy and spectrophotometry data showed that WO3 NPs induce hemolytic activity. This effect is probably attributed to the direct interaction of the nanoparticles with the RBCs, resulting in the oxidative stress, membrane injury, and subsequent hemolysis.
Ключевые слова:
tungsten oxide nanoparticles, human erythrocytes, hemolysis.
Поступила в редакцию: 10.02.2019 Исправленный вариант: 21.02.2019
Образец цитирования:
A. L. Popov, I. V. Savintseva, N. R. Popova, T. O. Shekunova, O. S. Ivanova, A. B. Shcherbakov, D. A. Kozlov, V. K. Ivanov, “Pvp-stabilized tungsten oxide nanoparticles (WO$_3$) nanoparticles cause hemolysis of human erythrocytes in a dose-dependent manner”, Наносистемы: физика, химия, математика, 10:2 (2019), 199–205
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/nano433 https://www.mathnet.ru/rus/nano/v10/i2/p199
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Страница аннотации: | 112 | PDF полного текста: | 124 |
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