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Эта публикация цитируется в 2 научных статьях (всего в 2 статьях)
CHEMISTRY AND MATERIAL SCIENCE
PVP-stabilized tungsten oxide nanoparticles inhibit proliferation of NCTC L929 mouse fibroblasts via induction of intracellular oxidative stress
A. L. Popova, A. M. Ermakova, T. O. Shekunovabc, A. B. Shcherbakovd, O. N. Ermakovaa, O. S. Ivanovac, N. R. Popovaa, A. Ye. Baranchikovc, V. K. Ivanovc a Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences,
Pushchino, Moscow region, 142290, Russia
b Lomonosov Moscow State University, Moscow, 119991, Russia
c Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russia
d Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine,
Kyiv, D0368, Ukraine
Аннотация:
In this study, photochromic PVP-stabilized tungsten oxide nanoparticles (WO$_{3-x}$ NPs) were shown to exhibit a dose-dependent cytotoxic effect on mouse fibroblasts in vitro. WO$_{3-x}$ NPs reduce viability and proliferative activity of the cells via induction of intracellular oxidative stress leading to apoptosis and cell death. WO$_{3-x}$ NPs modulate the mRNA expression of a wide range of genes responsible for oxidative stress and the cell redox-system.
Ключевые слова:
tungsten oxide nanoparticles, cytotoxicity, apoptosis, fibroblasts.
Поступила в редакцию: 03.01.2019 Исправленный вариант: 22.01.2019
Образец цитирования:
A. L. Popov, A. M. Ermakov, T. O. Shekunova, A. B. Shcherbakov, O. N. Ermakova, O. S. Ivanova, N. R. Popova, A. Ye. Baranchikov, V. K. Ivanov, “PVP-stabilized tungsten oxide nanoparticles inhibit proliferation of NCTC L929 mouse fibroblasts via induction of intracellular oxidative stress”, Наносистемы: физика, химия, математика, 10:1 (2019), 92–101
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/nano420 https://www.mathnet.ru/rus/nano/v10/i1/p92
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