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Эта публикация цитируется в 1 научной статье (всего в 1 статье)
CHEMISTRY AND MATERIAL SCIENCE
Evaluation of antibacterial potential of bilirubin nanoparticles against Staphylococcus aureus and Escherichia coli
Dhaval J. Kamothia, Vinay Kanta, Vinod Kumara, Vinay G. Joshib, Rajesh Chhabrac a Department of Veterinary Pharmacology & Toxicology, COVS, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, India
b Department of Animal Biotechnology, COVS, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, India
c College Central Laboratory, COVS, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, India
Аннотация:
Antimicrobial resistance is a major emerging clinical and public health issue across the globe. Nanotechnology is an emerging field and developing area of scientific interest in the world. Earlier reports showed in vivo antibacterial activity of bilirubin. Therefore, in present study, bilirubin nanoparticles (BNP) were synthesized of $\sim$100 – 150 nm, spherical shape and negative charge. Antibacterial activity of BNPs at different concentrations (0.03, 0.1 and 0.3%) was evaluated by agar well diffusion method against the gram-positive i.e. S. aureus and gram-negative i.e. E. coli bacteria. Tetracycline and enrofloxacin used as positive control. Tetracycline and Enrofloxacin at different concentrations exhibited zones of inhibition against both S. aureus and E. coli. However, BNPs as well as bulk bilirubin showed no in vitro antibacterial effect on S. aureus and E. coli, however, testing by broth method and at higher concentration as well as against other microorganisms can be explored in future.
Ключевые слова:
Bilirubin nanoparticles, S. aureus, E. coli, antibacterial activity.
Поступила в редакцию: 27.01.2022 Исправленный вариант: 21.05.2022 Принята в печать: 22.05.2022
Образец цитирования:
Dhaval J. Kamothi, Vinay Kant, Vinod Kumar, Vinay G. Joshi, Rajesh Chhabra, “Evaluation of antibacterial potential of bilirubin nanoparticles against Staphylococcus aureus and Escherichia coli”, Наносистемы: физика, химия, математика, 13:3 (2022), 342–348
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/nano1116 https://www.mathnet.ru/rus/nano/v13/i3/p342
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Страница аннотации: | 51 | PDF полного текста: | 19 |
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