Аннотация:
The Buchwald–Hartwig cross-coupling of 5-bromo-4-(furan-2-yl)pyrimidine with various anilines afforded the corresponding new 5-(arylamino)pyrimidines, the reaction being accelerated by microwave irradiation. Most of the obtained compounds proved to possess a high bacteriostatic in vitro effect against Mycobacterium tuberculosis H37Rv, Neisseria gonorrhoeae, and Staphylococcus aureus including Methicillin-resistant strain, which is stronger than that of the commercial drug Spectinomycin.
Образец цитирования:
E. V. Verbitskiy, S. A. Baskakova, D. V. Belyaev, D. V. Vakhrusheva, N. I. Eremeeva, G. L. Rusinov, V. N. Charushin, “Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity”, Mendeleev Commun., 31:2 (2021), 210–212
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc881
https://www.mathnet.ru/rus/mendc/v31/i2/p210
Эта публикация цитируется в следующих 12 статьяx:
Yu. O. Edilova, E. A. Osipova, Yu. S. Kudyakova, P. A. Slepukhin, V. I. Saloutin, D. N. Bazhin, “Polyfunctionalized pyrimidines based on 1,2,4-triketones”, Russ Chem Bull, 73:7 (2024), 1968
Leydi M. Moreno, Jairo Quiroga, Rodrigo Abonia, María del P. Crespo, Carlos Aranaga, Luis Martínez-Martínez, Maximiliano Sortino, Mauricio Barreto, María E. Burbano, Braulio Insuasty, “Synthesis of Novel Triazine-Based Chalcones and 8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepines as Potential Leads in the Search of Anticancer, Antibacterial and Antifungal Agents”, IJMS, 25:7 (2024), 3623
Valery N. Charushin, Mikhail V. Varaksin, Egor V. Verbitskiy, Oleg N. Chupakhin, Advances in Heterocyclic Chemistry, 144, 2024, 1
K. A. Gomonov, V. V. Pelipko, I. A. Litvinov, S. I. Selivanov, R. I. Baichurin, S. V. Makarenko, “Nitrofuran-3-carboxylates: synthesis and structure”, Mendeleev Commun., 34:3 (2024), 398–400
Simeon Dimitrov, Ivaylo Slavchev, Rumyana Simeonova, Milka Mileva, Tania Pencheva, Stanislav Philipov, Almira Georgieva, Elina Tsvetanova, Yoanna Teneva, Nadezhda Rimpova, Georgi Dobrikov, Violeta Valcheva, “Evaluation of Acute and Sub-Acute Toxicity, Oxidative Stress and Molecular Docking of Two Nitrofuranyl Amides as Promising Anti-Tuberculosis Agents”, Biomolecules, 13:8 (2023), 1174
Halina Kwiecień, Progress in Heterocyclic Chemistry, 34, 2023, 209
Pradnya Patil, Afrin Ansari, Savita. J. Tauro, Sahaya Nadar, “Green Recipes for Pyrimidine”, COS, 20:6 (2023), 678
Matteo Mori, Andrea Tresoldi, Stefania Villa, Giulia Cazzaniga, Marco Bellinzoni, Fiorella Meneghetti, “5-(4-Nitrophenyl)furan-2-carboxylic Acid”, Molbank, 2022:4 (2022), M1515
Gusein A. Sadykhov, Danila V. Belyaev, Diana V. Vakhrusheva, Natalya I. Eremeeva, Ekaterina E. Khramtsova, Marina G. Pervova, Gennady L. Rusinov, Egor V. Verbitskiy, Oleg N. Chupakhin, Valery N. Charushin, “New Approach to Biologically Active Indolo[2,3‐b]quinoxaline Derivatives through Intramolecular Oxidative Cyclodehydrogenation”, ChemistrySelect, 7:18 (2022)
Alexander Sapegin, Elizaveta Rogacheva, Lyudmila Kraeva, Maxim Gureev, Marine Dogonadze, Tatiana Vinogradova, Petr Yablonsky, Saeed Balalaie, Sergey V. Baykov, Mikhail Krasavin, “Novel 5-Nitrofuran-Tagged Imidazo-Fused Azines and Azoles Amenable by the Groebke–Blackburn–Bienaymé Multicomponent Reaction: Activity Profile against ESKAPE Pathogens and Mycobacteria”, Biomedicines, 10:9 (2022), 2203
M. Yu. Krasavin, A. A. Shetnev, V. A. Panova, S. A. Ivanovskii, S. A. Kalinin, T. Vinogradova, V. V. Sharoyko, P. Yablonsky, “Hetaryl- and heteroarylvinyl-substituted nitrofurans identified as non-cytotoxic selective antitubercular agents”, Mendeleev Commun., 32:4 (2022), 452–453
K. E. Shepelenko, K. A. Nikolaeva, I. G. Gnatiuk, O. G. Garanzha, A. A. Alexandrov, M. E. Minyaev, V. M. Chernyshev, “Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives”, Mendeleev Commun., 32:4 (2022), 485–487
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