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Эта публикация цитируется в 3 научных статьях (всего в 3 статьях)
Synthesis of 2-amino-3,6-di(het)arylpyridines from 5-cyano-3,6-di(het)aryl-1,2,4-triazines and arylhydrazines via the SNipso/aza-Diels–Alder reaction sequence
A. P. Krinochkinab, M. R. Gudab, A. Rammohanb, D. S. Kopchukab, I. L. Nikonovab, E. D. Ladinb, S. Santrab, I. N. Egorovb, G. V. Zyryanovab, O. N. Chupakhinb
a I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
b Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
Аннотация:
Reaction between 5-cyano-3,6-di(het)aryl-1,2,4-triazines and arylhydrazines with the following aza-Diels–Alder autoclave reaction affords hardly available 2-amino-3,6-di(het)arylpyridines in up to 67% yield after two steps and in 75% yield for the one-pot way. The compounds obtained can be promising for medicinal chemistry.
Ключевые слова:
2-aminopyridines, 6-amino-2,2′-bipyridines, 1,2,4-triazines, arylhydrazines, ipso-substitution, aza-Diels-Alder reaction,
autoclave processes.
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc779
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