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Эта публикация цитируется в 3 научных статьях (всего в 3 статьях)
One-pot synthesis of cyclopentane-fused 5'-aryl-4-cycloalkylamino-2,2'-bipyridines via the aza-Diels–Alder/SN
ipso reactions
A. P. Krinochkinab, E. S. Starnovskayaab, M. I. Valievaab, D. S. Kopchukab, S. Santrab, P. A. Slepukhinab, G. V. Zyryanovab, A. Majeec, O. N. Chupakhinab
a I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
b Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
c Department of Chemistry, Visva-Bharati University, Santiniketan, West Bengal, India
Аннотация:
One-pot synthesis of cyclopentane-fused 5'-aryl-4-cycloalkylamino-2,2'-bipyridines based on the neat (200 °C) reaction of 3-(4-bromopyridin-2-yl)-1,2,4-triazines with enamines is reported. In the course of the transformation, consecutive aza-Diels–Alder reaction and nucleophilic
substitution of bromine atom under the action of the liberating amine occur. The possibility of the solvent- and catalyst-free replacement of 4-positioned bromine atom in 2,2'-bipyridines by amino moieties was demonstrated.
Ключевые слова:
amino-2,2'-bipyridines, 1,2,4-triazines, aza-Diels–Alder reaction, ipso-substitution, solvent-free reaction, one-pot synthesis, enamines.
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc691
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