Synthesis of spiro[chromane-2,4'-pyrimidines] by condensation of 6-styryldihydropyrimidin-2-ones with resorcinols

Substituted spiro[chromane-2,4'-pyrimidines] were obtained by the acid-catalyzed reaction between 4-aryl-6-styryl-3,4-dihydropyrimidin-2(1H)-ones and resorcinols. The structure of the resulting diastereomeric 4,6'-diaryl-7-hydroxy-5',6'-dihydro-1'H-spiro[chromane-2,4'-pyrimidin]-2'(3'H)-ones has been determined by 2D spectroscopy and single-crystal X-ray diffraction analysis