Аннотация:
Core–shell nanoparticles with poly(lactide-co-glycolide) cores and human serum albumin shells (PLGA/HSA NPs) were prepared by three methods: by interfacial embedding of HSA in the PLGA NP surface during their formation and by adsorption or conjugation of HSA on pre-prepared PLGA NPs. All methods yielded PLGA/HSA NPs with a size of 130–150 nm and a narrow size distribution. In vitro fluorescence microscopy revealed the integrity of all core–shell systems when internalized in GL261 cells.
Ключевые слова:
core–shell nanoparticles, PLGA, human serum albumin, drug delivery systems, intracellular internalization, laser scanning confocal microscopy, LSCM.
Тип публикации:
Статья
Язык публикации: английский
Образец цитирования:
J. O. Kotova, N. S. Osipova, J. A. Malinovskaya, P. A. Melnikov, S. E. Gelperina, “Properties of core–shell nanoparticles based on PLGA and human serum albumin prepared by different methods”, Mendeleev Commun., 33:5 (2023), 676–678
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc492
https://www.mathnet.ru/rus/mendc/v33/i5/p676
Эта публикация цитируется в следующих 3 статьяx:
A. A. Skuredina, E. V. Kudryashova, Mendeleev Commun., 35:1 (2025), 76–78
Lianguo Wang, Pei Wang, Yifan Liu, Muhammad Atae Mustafa Mahayyudin, Rong Li, Weilun Zhang, Yilan Zhan, Zhihua Li, “The Effect of Different Factors on Poly(lactic-co-glycolic acid) Nanoparticle Properties and Drug Release Behaviors When Co-Loaded with Hydrophilic and Hydrophobic Drugs”, Polymers, 16:7 (2024), 865
Tatyana Kovshova, Julia Malinovskaya, Julia Kotova, Marina Gorshkova, Lyudmila Vanchugova, Nadezhda Osipova, Pavel Melnikov, Veronika Vadekhina, Alexey Nikitin, Yulia Ermolenko, Svetlana Gelperina, “Core–Shell PLGA Nanoparticles: In Vitro Evaluation of System Integrity”, Biomolecules, 14:12 (2024), 1601
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