Аннотация:
We demonstrated covalent cross-linking of two or three protein molecules specifically at the C-terminus by sortase-catalyzed conjugation of recombinant proteins with conformationally rigid-flexible tetraantennary templates, where structure of the antenna is [Gly-Gly-(N-CH2COOH)Gly]nCH2–.
Ключевые слова:
bioconjugation, sortase, protein A, oligoglycine, protein homooligomerization.
Образец цитирования:
T. D. Melikhova, N. V. Bovin, A. D. Antipov, M. N. Tereshin, R. H. Ziganshin, A. B. Tuzikov, “Sortase-promoted synthesis of homooligomers from a monomeric protein”, Mendeleev Commun., 33:5 (2023), 624–626
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc476
https://www.mathnet.ru/rus/mendc/v33/i5/p624
Эта публикация цитируется в следующих 2 статьяx:
T. D. Melikhova, N. V. Bovin, N. S. Shoshina, T. V. Bobik, L. A. Gavrilov, M. A. Sablina, E. M. Rapoport, V. N. Stepanenko, A. B. Tuzikov, Mendeleev Commun., 35:2 (2025), 136–138
I. M. Ryzhov, P. S. Obukhova, O. E. Galanina, E. M. Rapoport, N. S. Egorova, N. V. Bovin, A. B. Tuzikov, “Synthesis of pseudocyclic peptide of protein S of SARS-CoV-2 and its interaction with diagnostically significant antibodies of COVID-19 patients”, Mendeleev Commun., 34:4 (2024), 499–501
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