Эта публикация цитируется в 1 научной статье (всего в 1 статье)
Communications
New N1-(4-aryloxybenzyl)uracils containing N3-positioned 4-(trimethyleneoxy)benzoic acid moiety, and study of their antiviral activity against SARS-CoV-2 and influenza virus
Аннотация:
New title uracil derivatives, 4-{3-[2,6-dioxo-3-(4-aryl-oxybenzyl)-3,6-dihydropyrimidin-1(2H)-yl]propoxy}benzoic acids and their butoxy homologues, were obtained in three steps using 2,4-bis(trimethylsilyloxy)pyrimidine, 4-aryloxy-benzyl bromides and methyl 4-(ω-bromoalkoxy)benzoates as the key reactants. The compounds were studied as inhibitors of H1N1 influenza virus and SARS-CoV-2 R replication in MDCK and Vero E6 cell cultures, respectively, which revealed that the tested compounds had high levels of anti-SARS-CoV-2 activity.
Образец цитирования:
M. S. Novikov, M. P. Paramonova, I. M. Kirillov, O. A. Smirnova, A. L. Khandazhinskaya, A. O. Chizhov, S. N. Kochetkov, A. V. Ivanov, I. F. Fedyakina, “New N1-(4-aryloxybenzyl)uracils containing N3-positioned 4-(trimethyleneoxy)benzoic acid moiety, and study of their antiviral activity against SARS-CoV-2 and influenza virus”, Mendeleev Commun., 33:4 (2023), 537–538
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc452
https://www.mathnet.ru/rus/mendc/v33/i4/p537
Эта публикация цитируется в следующих 1 статьяx:
O. A. Zhupikova, O. I. Yarovaya, M. K. Marenina, Yu. V. Meshkova, S. V. Belenkaya, D. N. Shcherbakov, A. V. Zaykovskaya, O. V. Pyankov, V. V. Zarubaev, M. G. Mikhalsky, A. Yu. Fedorov, S. G. Arkhipov, V. I. Potkin, I. A. Kolesnik, A. V. Ivanov, N. F. Salakhutdinov, M. V. Khvostov, Mendeleev Commun., 35:2 (2025), 145–147
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