First comb-like copolymer of poly(ethyl 2-cyanoacrylate) grafted as a side-chain to dextran

The first comb-like cyanoacrylic copolymer was synthesized by anionic polymerization of ethyl 2-cyanoacrylate in an aqueous solution of dextran of M_w = 50 ± 5 kDa. The copolymer was explored by NMR and Fourier IR spectroscopy, as well as by MALDI-TOF mass-spectrometry methods. It contains up to 10 cyanoacrylate units grafted to anhydroglucose cycles of dextran main chain, multi- substituted glycose units were not detected.