Heteropoly metallophosphoric acid-catalyzed Prins-type cyclizations in the synthesis of functionalized 8-oxabicyclo[5.4.0]undecanes

Heteropoly metallophosphoric acid-catalyzed microwave-assisted Prins cyclizations of 4-cyano-4-phenyl-7-vinylcycloheptanol with carbonyl compounds affords functionalized 8-oxabicyclo[5.4.0]undecanes in good yields and with high stereoselectivity.