Catalytic amination in the synthesis of hybrid polymacrocycles comprising porphyrin and azacrown ether moieties

Pd⁰-catalyzed amination of 3-bromobenzyl-substituted azacrown ethers with propane-1,3-diamine affords the 3-(3-aminopropyl)benzyl derivatives, whose reaction with meso-(bromophenyl)-substituted porphyrins leads to bis- and trismacrocyclic conjugates.