Аннотация:
The azido-Ugi reaction of methyl maleopimarate N-(2- aminoethyl) imide with isocyanides, paraformaldehyde and trimethylsilyl azide in one step leads to 1,5-disubstituted diterpene bis-tetrazoles. The compounds demonstrate selective cytotoxicity against NCI-60 cancer cell panel.
Образец цитирования:
A. A. Smirnova, E. V. Tretyakova, O. B. Kazakova, “Inhibiting the cancer cell growth by maleopimarate amino imide bis-tetrazoles synthesized via the azido-Ugi reaction”, Mendeleev Commun., 34:4 (2024), 509–510
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc169
https://www.mathnet.ru/rus/mendc/v34/i4/p509
Эта публикация цитируется в следующих 2 статьяx:
Anna Smirnova, Elena Tretyakova, Oxana Kazakova, “New Cytotoxic α‐Aminoacylamide and bis‐1,5‐Disubstituted Tetrazole Adducts From Amino‐Diterpene Molecules by Ugi Reaction”, Chem Biol Drug Des, 104:3 (2024)
Elena Tretyakova, Anna Smirnova, Denis Babkov, Oxana Kazakova, “Derivatization of Abietane Acids by Peptide-like Substituents Leads to Submicromolar Cytotoxicity at NCI-60 Panel”, Molecules, 29:15 (2024), 3532
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