Аннотация:
5,7-Dimethyl-2,3-dinitropyrazolo[1,5-a]pyrimidine in reaction with N-, S- and O-nucleophiles under mild conditions undergoes regioselective nucleophilic substitution of the 2-positioned nitro group, which provides an access to a library of 2-R-3-nitropyrazolo[1,5-a]pyrimidines.
Образец цитирования:
T. K. Shkineva, I. A. Vatsadze, I. L. Dalinger, “A new general synthesis of functionally substituted pyrazolo[1,5-a]pyrimidines”, Mendeleev Commun., 29:4 (2019), 429–431
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc1548
https://www.mathnet.ru/rus/mendc/v29/i4/p429
Эта публикация цитируется в следующих 6 статьяx:
Tatyana K. Shkineva, Svetlana A. Krasnova, Igor L. Dalinger, “The first example of a cine-substitution in a series of 1,3-dinitropyrazoles”, Chem Heterocycl Comp, 60:5-6 (2024), 257
T. K. Shkineva, O. V. Serushkina, I. A. Vatsadze, T. E. Khoranyan, I. L. Dalinger, “Synthesis of 2,5-disubstituted pyrazolyl-1,3,4-oxadiazoles by the Huisgen reaction”, Russ Chem Bull, 71:8 (2022), 1737
Galal H. Elgemeie, Rasha A. Azzam, Wafaa A. Zaghary, Mohammed A. Khedr, Gihad E. Elsherif, “Medicinal Chemistry of Pyrazolopyrimidine Scaffolds Substituted with Different Heterocyclic Nuclei”, CPD, 28:41 (2022), 3374
Aisha Y. Hassan, Samiha A. El-Sebaey, Moshira A. El Deeb, Mona S. Elzoghbi, “Potential antiviral and anticancer effect of imidazoles and bridgehead imidazoles generated by HPV-Induced cervical carcinomas via reactivating the P53/ pRb pathway and inhibition of CA IX”, Journal of Molecular Structure, 1230 (2021), 129865
Ma'mon M. Hatmal, Omar Abuyaman, Mutasem Taha, “Docking-generated multiple ligand poses for bootstrapping bioactivity classifying Machine Learning: Repurposing covalent inhibitors for COVID-19-related TMPRSS2 as case study”, Computational and Structural Biotechnology Journal, 19 (2021), 4790
Tatyana K. Shkineva, Irina A. Vatsadze, Tigran E. Khoranyan, Dmitry L. Lipilin, Alla N. Pivkina, Igor L. Dalinger, “Synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazole nitro derivatives”, Chem Heterocycl Comp, 57:7-8 (2021), 828
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