L. M. Nguyen, H. H. Truong, V. N. Khrustalev, S. T. Truong, D. T. Nguyen, V. T. Tran, S. T. Mai, V. T. Tran, A. T. Le, “Synthesis and biological evaluation of novel phane-structured diazacrowns containing γ-piperidone and pyridine rings”, Mendeleev Commun., 30:6 (2020), 753

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Mendeleev Communications

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ЖУРНАЛЫ ПЕРСОНАЛИИ ОРГАНИЗАЦИИ КОНФЕРЕНЦИИ СЕМИНАРЫ ВИДЕОТЕКА ПАКЕТ AMSBIB

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Mendeleev Communications, 2020, том 30, выпуск 6, страницы 753–755
DOI: https://doi.org/10.1016/j.mencom.2020.11.021 (Mi mendc1314)

Эта публикация цитируется в 5 научных статьях (всего в 5 статьях)

Communications

Synthesis and biological evaluation of novel phane-structured diazacrowns containing γ-piperidone and pyridine rings

L. M. Nguyen^ab, H. H. Truong^c, V. N. Khrustalev^cd, S. T. Truong^a, D. T. Nguyen^a, V. T. Tran^a, S. T. Mai^a, V. T. Tran^a, A. T. Le^a

^a Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Hoan Kiem, Hanoi, Vietnam
^b Faculty of Pharmacy, Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen City, Vietnam
^c Peoples Friendship University of Russia (RUDN University), Moscow, Russian Federation
^d N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

PDF полного текста (789 kB) Список цитирования (5)

DOI: https://doi.org/10.1016/j.mencom.2020.11.021

Graphic abstract: Synthesis and biological evaluation of novel phane-structured diazacrowns containing γ-piperidone and pyridine rings

Аннотация: Six novel phane-structured diazacrowns containing γ-piperidone and pyridine rings were synthesized from podand 2-+,6-bis(2-formylphenoxymethyl)pyridine, with the γ-piperidone moiety having been constructed in the course of its domino condensation with simple ketones and ammonium acetate. The compounds were tested in vitro for antimicrobial and cytotoxic activity against four human cancer cell lines (Hep-G2, RD, MCF-7, Lu-1) and the Vero cell line. X-Ray structure study of one representative compound revealed its rac-1RS,23SR,24RS,26SR configuration.

Ключевые слова: diazacrownophane, γ-piperidone, pyridine, cytotoxicity, antimicrobial, domino condensation.

Тип публикации: Статья

Язык публикации: английский

*Дополнительные материалы:*
		Supplementary_data_1.pdf	(3.9 Mb)

Образец цитирования: L. M. Nguyen, H. H. Truong, V. N. Khrustalev, S. T. Truong, D. T. Nguyen, V. T. Tran, S. T. Mai, V. T. Tran, A. T. Le, “Synthesis and biological evaluation of novel phane-structured diazacrowns containing γ-piperidone and pyridine rings”, Mendeleev Commun., 30:6 (2020), 753–755

Образцы ссылок на эту страницу:

https://www.mathnet.ru/rus/mendc1314

https://www.mathnet.ru/rus/mendc/v30/i6/p753

Эта публикация цитируется в следующих 5 статьяx:

Dao T. Nhung, Nguyen N. Tram, Pham T. T. Tam, Kseniia A. Alekseeva, Victor N. Khrustalev, Dang T. Hoang, Le. T. Duan, Le. T. Anh, “Synthesis, α‐Glucosidase Inhibitory Activity, and Molecular Docking Studies of Tri(benzo)‐5‐azacrownophanes with a γ‐Piperidone Moiety”, ChemistrySelect, 8:25 (2023)
M. A. Katkova, G. S. Zabrodina, R. V. Rumyantcev, G. Yu. Zhigulin, M. S. Muravyeva, M. P. Shurygina, S. A. Chesnokov, S. Yu. Ketkov, “Halogen-substituted salicylhydroximate copper(II) metallacrowns: from synthesis and structures to novel applications”, Mendeleev Commun., 33:1 (2023), 37–40
Tung H. To, Dang B. Tran, Thang C. Pham, Phong D. Tran, “A new approach to pyrimidine-type heterocycles based on Petrenko–Kritschenko synthesis”, Chem Heterocycl Comp, 58:11 (2022), 608
Thanh Van Tran Thi, Manh Linh Nguyen, Tien Dat Nguyen, The Duan Le, Hong Hieu Truong, Victor N. Khrustalev, Tuan Anh Le, “Synthesis of the First Dithiaaza-17-Crown-5 Ethers Containing Piperidin-4-One Subunit”, Chem Heterocycl Comp, 57:10 (2021), 1057
N. T. Dao, D. T. Nguyen, L. M. Nguyen, V. T. T. Tran, T. T. Do, A. T. Le, “Synthesis of Dithiacrown Ethers and Evaluation of Their Cytotoxic Activity”, ChemistrySelect, 6:40 (2021), 11081

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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