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Письма в Журнал экспериментальной и теоретической физики, 2011, том 93, выпуск 1, страницы 43–1
(Mi jetpl1802)
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Эта публикация цитируется в 1 научной статье (всего в 1 статье)
БИОФИЗИКА
Are the complex distributed genetic networks inherently oscillatory and chaotic?
V. P. Zhdanovab a Boreskov Institute of Catalysis RAS, 630090 Novosibirsk, Russia
b Department of Applied Physics, Chalmers University of Technology, S-412 96 Göteborg, Sweden
Аннотация:
Complex mRNA-protein networks with distributed regulation of gene transcription are often mimicked by random Boolean networks. According to this mapping, the gene-expression kinetics are expected to depend strongly on the network connectivity, $m$. Specifically, the kinetics are predicted to be oscillatory or chaotic for $m>2$. We analyze this problem in more detail by using an accurate model explicitly describing the mRNA-protein interplay with randomly organized transcriptional regulation. Contrary to the expectations, our mean-field calculations and Monte Carlo simulations performed for $m=1$, $2$ and $4$ show that oscillations and chaos are lacking irrespective of $m$.
Поступила в редакцию: 16.11.2010
Образец цитирования:
V. P. Zhdanov, “Are the complex distributed genetic networks inherently oscillatory and chaotic?”, Письма в ЖЭТФ, 93:1 (2011), 43–1; JETP Letters, 93:1 (2011), 41–45
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/jetpl1802 https://www.mathnet.ru/rus/jetpl/v93/i1/p43
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Страница аннотации: | 218 | PDF полного текста: | 78 | Список литературы: | 52 |
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