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Письма в Журнал экспериментальной и теоретической физики, 2010, том 92, выпуск 6, страницы 454–459
(Mi jetpl1424)
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Эта публикация цитируется в 6 научных статьях (всего в 6 статьях)
БИОФИЗИКА
Stochastic bursts in the kinetics of gene expression with regulation by long non-coding RNAs
V. P. Zhdanovab a Boreskov Institute of Catalysis, Russian Academy of Sciences, Novosibirsk, Russia
b Department of Applied Physics, Chalmers University of Technology, Göteborg, Sweden
Аннотация:
One of the main recent breakthroughs in cellular biology is a discovery of numerous non-coding RNAs (ncRNAs). We outline abilities of long ncRNAs and articulate that the corresponding kinetics may frequently exhibit stochastic bursts. For example, we scrutinize one of the generic cases when the gene transcription is regulated by competitive attachment of ncRNA and protein to a regulatory site. Our Monte Carlo simulations show that in this case one can observe huge long transcriptional bursts consisting of short bursts.
Поступила в редакцию: 02.08.2010
Образец цитирования:
V. P. Zhdanov, “Stochastic bursts in the kinetics of gene expression with regulation by long non-coding RNAs”, Письма в ЖЭТФ, 92:6 (2010), 454–459; JETP Letters, 92:6 (2010), 410–415
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/jetpl1424 https://www.mathnet.ru/rus/jetpl/v92/i6/p454
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