|
Vestnik SamGU. Estestvenno-Nauchnaya Ser., 2009, Issue 6(72), Pages 177–182
(Mi vsgu270)
|
|
|
|
Biology
Concerning the mutagenic activity of structural analogues of natural nucleosydes
E. S. Seleznevaa, Z. P. Belousovaa, I. A. Medvedevab a Samara State University
b The center of Hygiene and Epidemiology in Sverdlovsk Region, CEF FGUZ
(published under the terms of the Creative Commons Attribution 4.0 International License)
Abstract:
The mutagenic activity of $1-\beta -D$ eritrofuranozulbensimidazolide, $1-\beta -D$ eritrofuranozulbensotriazolide, $1-\beta -D$ ribofuranozylbensotriazolide on Drosophila melanogaster imago in non-toxic dozes and in LD50. It was shown that the number of induced recessive lethal mutations was not dependent of tested doses but the number of dominant lethal mutations was reliably increased for LD50. The tested substances induced more dominant lethal mutations in females than in males.
Keywords:
Drosophila melanogaster, dominant and recessive lethal mutations, structural analogues of natural nucleosides.
Received: 15.05.2009 Revised: 15.05.2009
Citation:
E. S. Selezneva, Z. P. Belousova, I. A. Medvedeva, “Concerning the mutagenic activity of structural analogues of natural nucleosydes”, Vestnik Samarskogo Gosudarstvennogo Universiteta. Estestvenno-Nauchnaya Seriya, 2009, no. 6(72), 177–182
Linking options:
https://www.mathnet.ru/eng/vsgu270 https://www.mathnet.ru/eng/vsgu/y2009/i6/p177
|
Statistics & downloads: |
Abstract page: | 89 | Full-text PDF : | 72 | References: | 27 | First page: | 1 |
|