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Proceedings of the Yerevan State University, series Physical and Mathematical Sciences, 2017, Volume 51, Issue 2, Pages 187–192 (Mi uzeru382)  
Physics

Calculation of central moments of differential melting curve of DNA molecule

R. S. Ghazaryana, S. N. Hakobyanb, M. A. Shahinyanc

a Chair of Molecular Physics YSU, Armenia
b Department of Mechanical Engineering SEUA, Armenia
c Chair of Biophysics YSU, Armenia
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Abstract: Central moments of function of the differential melting curve (DMC) of DNA have been calculated through expansion of block DNA DMC to Gaussian components. Calculations showed that the first moment of DNA DMC characterizes the melting temperature, the second is DNA melting interval. Central moments of the third and fourth orders characterize distribution of nucleotides along DNA chain. It was shown that the distribution of nucleotides along DNA chain differs from quasi-arbitrary distribution.
Keywords: differential melting curve, central moments of DMC of DNA.
Received: 28.11.2016
Accepted: 28.02.2017
Document Type: Article
Language: English
Citation: R. S. Ghazaryan, S. N. Hakobyan, M. A. Shahinyan, “Calculation of central moments of differential melting curve of DNA molecule”, Proceedings of the YSU, Physical and Mathematical Sciences, 51:2 (2017), 187–192
Citation in format AMSBIB
\Bibitem{GhaHakSha17}
\by R.~S.~Ghazaryan, S.~N.~Hakobyan, M.~A.~Shahinyan
\paper Calculation of central moments of differential melting curve of DNA molecule
\jour Proceedings of the YSU, Physical and Mathematical Sciences
\yr 2017
\vol 51
\issue 2
\pages 187--192
\mathnet{http://mi.mathnet.ru/uzeru382}
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