Proceedings of the Yerevan State University, series Physical and Mathematical Sciences
RUS  ENG    JOURNALS   PEOPLE   ORGANISATIONS   CONFERENCES   SEMINARS   VIDEO LIBRARY   PACKAGE AMSBIB  
General information
Latest issue
Archive

Search papers
Search references

RSS
Latest issue
Current issues
Archive issues
What is RSS



Proceedings of the YSU, Physical and Mathematical Sciences:
Year:
Volume:
Issue:
Page:
Find






Personal entry:
Login:
Password:
Save password
Enter
Forgotten password?
Register


Proceedings of the Yerevan State University, series Physical and Mathematical Sciences, 2017, Volume 51, Issue 1, Pages 66–70 (Mi uzeru333)  

This article is cited in 1 scientific paper (total in 1 paper)

Physics

Effect of ligand binding on functionality of DNA field-effect transistor

E. Sh. Mamasakhlisova, A. P. Antonyanb, A. A. Akopyanc

a Chair of Molecular Physics YSU, Armenia
b Chair of Biophysics YSU, Armenia
c Institute of Radiophysics and Electronics, Ashtarak, Armenia
Full-text PDF (300 kB) Citations (1)
References:
Abstract: Motivated by the prospects of developing DNA field-effect transistors, as tools for a variety of application fields such as medical diagnostics, environmental pollutants monitoring, biological weapons defense, and taking into account that the efficiency of DNA-sensors depends on the precise prediction of experimental parameters responsible for thermostability of nucleic acids duplexes and specific times of formation of DNA duplexes, we analyze the factors influencing both the thermodynamics of hybridization and the stability of DNA–DNA and DNA–RNA duplexes. In this work the case of competition-free DNA hybridization is analyzed. It is shown how the intercalating ligands effectively increase the binding constant for the target sequences and thus affects the sensitivity of the DNA-chip.
Keywords: ligand binding, thermostability, hybridization, DNA-chip.
Received: 01.12.2016
Revised: 30.01.2017
Document Type: Article
Language: English
Citation: E. Sh. Mamasakhlisov, A. P. Antonyan, A. A. Akopyan, “Effect of ligand binding on functionality of DNA field-effect transistor”, Proceedings of the YSU, Physical and Mathematical Sciences, 51:1 (2017), 66–70
Citation in format AMSBIB
\Bibitem{MamAntAko17}
\by E.~Sh.~Mamasakhlisov, A.~P.~Antonyan, A.~A.~Akopyan
\paper Effect of ligand binding on functionality of DNA field-effect transistor
\jour Proceedings of the YSU, Physical and Mathematical Sciences
\yr 2017
\vol 51
\issue 1
\pages 66--70
\mathnet{http://mi.mathnet.ru/uzeru333}
Linking options:
  • https://www.mathnet.ru/eng/uzeru333
  • https://www.mathnet.ru/eng/uzeru/v51/i1/p66
  • This publication is cited in the following 1 articles:
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
    Proceedings of the Yerevan State University, series Physical and Mathematical Sciences
    Statistics & downloads:
    Abstract page:147
    Full-text PDF :35
    References:25
     
      Contact us:
     Terms of Use  Registration to the website  Logotypes © Steklov Mathematical Institute RAS, 2024