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Uspekhi Fizicheskikh Nauk, 2007, Volume 177, Number 5, Pages 535–552
DOI: https://doi.org/10.3367/UFNr.0177.200705c.0535
(Mi ufn463)
 

This article is cited in 34 scientific papers (total in 34 papers)

METHODOLOGICAL NOTES

Dynamic phase microscopy: is а 'dialogue' with the cell possible?

V. P. Tychinskii

Moscow State Institute of Radio Engineering, Electronics and Automatics (Technical University)
References:
Abstract: The metabolic component оf refractivity is considered as an example of а quantifying parameter for the 'vitality' of cells and organelles. It is shown that intracellular processes can be studied by the dynamic phase microscopy method, which provides real-time information in the form of local changes in the optical path difference. Preliminary results demonstrate the possibility of localizing а 'signal' and obtaining information under the signal – structure – function scheme and show prospects for conducting а 'dialogue' with а cell by real-time registering the way in which it responds to changes in external conditions. The mechanism underlying the dependence of refractivity on metabolic states is ехрlained by the contribution of bound water molecules.
Received: February 1, 2007
English version:
Physics–Uspekhi, 2007, Volume 50, Issue 5, Pages 513–528
DOI: https://doi.org/10.1070/PU2007v050n05ABEH006222
Bibliographic databases:
Document Type: Article
PACS: 07.60.-j, 87.16.-b, 87.64.-t
Language: Russian
Citation: V. P. Tychinskii, “Dynamic phase microscopy: is а 'dialogue' with the cell possible?”, UFN, 177:5 (2007), 535–552; Phys. Usp., 50:5 (2007), 513–528
Citation in format AMSBIB
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  • This publication is cited in the following 34 articles:
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
    Успехи физических наук Physics-Uspekhi
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