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Mathematical notes of NEFU, 2021, Volume 28, Issue 1, Pages 3–11
DOI: https://doi.org/10.25587/SVFU.2021.68.70.001
(Mi svfu306)
 

This article is cited in 1 scientific paper (total in 1 paper)

Mathematics

Phase portraits of two gene networks models

V. P. Golubyatnikovab, N. E. Kirillovaa

a Sobolev Institute of Mathematics, 4 Koptyug Avenue, Novosibirsk 630090, Russia
b Novosibirsk State University, 1 Pirogov Street, Novosibirsk 630090, Russia
Full-text PDF (424 kB) Citations (1)
Abstract: We construct mathematical models of functioning of two few-components gene networks which regulate circadian rhythmes in organisms by means of combinations of positive and negative feedbacks between components of these networks. Both models are represented in the form of non-linear dynamical systems of biochemical kinetics. It is shown that the phase portraits of both models contain exactly one equilibrium point each and in both cases for all values of parameters of these dynamical systems, eigenvalues of their linearization matrices at their equilibrium points are either negative or have negative real parts. Thus, these equilibrium points are stable. We construct their invariant neighborhoods and describe the behavior of trajectories of these systems. Biological interpretations of these results are given as well.
Keywords: gene networks models, non-linear dynamical systems, phase portrait, equilibrium point, stability, Vyshnegradskii criterion.
Received: 01.02.2021
Accepted: 26.02.2021
Bibliographic databases:
Document Type: Article
UDC: 514.745.82
Language: Russian
Citation: V. P. Golubyatnikov, N. E. Kirillova, “Phase portraits of two gene networks models”, Mathematical notes of NEFU, 28:1 (2021), 3–11
Citation in format AMSBIB
\Bibitem{GolKir21}
\by V.~P.~Golubyatnikov, N.~E.~Kirillova
\paper Phase portraits of two gene networks models
\jour Mathematical notes of NEFU
\yr 2021
\vol 28
\issue 1
\pages 3--11
\mathnet{http://mi.mathnet.ru/svfu306}
\crossref{https://doi.org/10.25587/SVFU.2021.68.70.001}
\elib{https://elibrary.ru/item.asp?id=45658536}
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  • This publication is cited in the following 1 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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    Mathematical notes of NEFU
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