Abstract:
The mechanoreceptors (in particular, macrochaetes) of drosophila pass three stages in its development (morphogenesis) whose genetic support is described in terms of gene networks. The key object of the gene networks of macrochaete morphogenesis is the achaete-scute (AS-C) complex of genes. Each mechanoreceptor develops from one parent cell distinguished by high concentration of the AS-C protein. The activity of this complex, which ensures the protein concentration critical for initiating morphogenesis, is determined by the central regulatory contour which includes a system of interactions among certain objects of the networks (genes and their products).
Citation:
T. A. Bukharina, V. P. Golubyatnikov, I. V. Golubyatnikov, D. P. Furman, “Mathematical modeling of the first phase of morphogenesis of mechanoreceptors in D. melanogaster”, Sib. Zh. Ind. Mat., 14:3 (2011), 14–19; J. Appl. Industr. Math., 6:2 (2012), 145–149
\Bibitem{BukGolGol11}
\by T.~A.~Bukharina, V.~P.~Golubyatnikov, I.~V.~Golubyatnikov, D.~P.~Furman
\paper Mathematical modeling of the first phase of morphogenesis of mechanoreceptors in {\it D.~melanogaster}
\jour Sib. Zh. Ind. Mat.
\yr 2011
\vol 14
\issue 3
\pages 14--19
\mathnet{http://mi.mathnet.ru/sjim678}
\mathscinet{http://mathscinet.ams.org/mathscinet-getitem?mr=2953771}
\transl
\jour J. Appl. Industr. Math.
\yr 2012
\vol 6
\issue 2
\pages 145--149
\crossref{https://doi.org/10.1134/S1990478912020020}
Linking options:
https://www.mathnet.ru/eng/sjim678
https://www.mathnet.ru/eng/sjim/v14/i3/p14
This publication is cited in the following 2 articles:
T. A. Bukharina, V. P. Golubyatnikov, D. P. Furman, “Gene network controlling the morphogenesis of D-melanogaster macrochaetes: An expanded model of the central regulatory circuit”, Russ. J. Dev. Biol., 47:5 (2016), 288–293
A. A. Akinshin, T. A. Bukharina, V. P. Golubyatnikov, D. P. Furman, “Matematicheskoe modelirovanie vzaimodeistviya dvukh kletok v proneiralnom klastere krylovogo imaginalnogo diska D. melanogaster”, Vestn. NGU. Ser. matem., mekh., inform., 14:4 (2014), 3–10