Loading [MathJax]/jax/output/CommonHTML/jax.js
Sibirskii Zhurnal Industrial'noi Matematiki
RUS  ENG    JOURNALS   PEOPLE   ORGANISATIONS   CONFERENCES   SEMINARS   VIDEO LIBRARY   PACKAGE AMSBIB  
General information
Latest issue
Archive
Impact factor

Search papers
Search references

RSS
Latest issue
Current issues
Archive issues
What is RSS



Sib. Zh. Ind. Mat.:
Year:
Volume:
Issue:
Page:
Find






Personal entry:
Login:
Password:
Save password
Enter
Forgotten password?
Register


Sibirskii Zhurnal Industrial'noi Matematiki, 2003, Volume 6, Number 2, Pages 64–80 (Mi sjim448)  

This article is cited in 42 scientific papers (total in 42 papers)

Problems in the theory of the functioning of genetic networks

V. A. Likhoshvaia, Yu. G. Matushkina, S. I. Fadeevb

a Institute of cytology and genetics Siberian Branch of the Russian Academy of Sciences
b Sobolev Institute of Mathematics, Siberian Branch of the Russian Academy of Sciences
References:
Abstract: We consider hypothetical genetic networks (HGN), which are theoretical objects constructed from elementary units of two types: matrix elements and regulatory mechanisms. Their operation is described by autonomous systems consisting ofn equations and related equations of a special form with retarded arguments. We give examples of HGN that have stable states, limit cycles, and attractors of a complicated nature. We introduce four classes of HGN that correspond to these regulatory relations and determine their canonical representations. For symmetric canonical HGN we formulate an (n,k)-criterion that enables us to predict in a certain parameter range their limit regimes of operation, i.e., to predict for the corresponding models the number and character of the stable limit states in them. In the case of HGN of the first and second classes, we formulate a conjecture on the one-to-one correspondence between the stable states and the 1-bases of directed structural graphs of these networks. In the case of HGN of the third and fourth classes, we formulate a conjecture on the one-to-one correspondence between the stable states and the 1m-bases of the directed structural graphs.
Received: 12.03.2003
Bibliographic databases:
UDC: 575:577.21:519.61
Language: Russian
Citation: V. A. Likhoshvai, Yu. G. Matushkin, S. I. Fadeev, “Problems in the theory of the functioning of genetic networks”, Sib. Zh. Ind. Mat., 6:2 (2003), 64–80
Citation in format AMSBIB
\Bibitem{LikMatFad03}
\by V.~A.~Likhoshvai, Yu.~G.~Matushkin, S.~I.~Fadeev
\paper Problems in the theory of the functioning of genetic networks
\jour Sib. Zh. Ind. Mat.
\yr 2003
\vol 6
\issue 2
\pages 64--80
\mathnet{http://mi.mathnet.ru/sjim448}
\mathscinet{http://mathscinet.ams.org/mathscinet-getitem?mr=2041576}
\zmath{https://zbmath.org/?q=an:1039.94543}
Linking options:
  • https://www.mathnet.ru/eng/sjim448
  • https://www.mathnet.ru/eng/sjim/v6/i2/p64
  • This publication is cited in the following 42 articles:
    1. D. A. Bratsun, M. D. Buzmakov, “Repressilyator s zapazdyvayuschei ekspressiei genov. Chast II. Stokhasticheskoe opisanie”, Kompyuternye issledovaniya i modelirovanie, 13:3 (2021), 587–609  mathnet  crossref
    2. S. D. Glyzin, A. Yu. Kolesov, N. Kh. Rozov, “On a mathematical model of the repressilator”, St. Petersburg Math. J., 33:5 (2022), 797–828  mathnet  crossref
    3. Lakhova T.N. Kazantsev V F. Lashin S.A. Matushkin Yu.G., “The Finding and Researching Algorithm For Potentially Oscillating Enzymatic Systems”, Vavilovskii Zhurnal Genet. Sel., 25:3 (2021), 318–330  crossref  isi  scopus
    4. Glyzin S.D. Kolesov A.Yu. Rozov N.Kh., “a New Approach to Gene Network Modeling”, Autom. Control Comp. Sci., 54:7 (2020), 655–684  crossref  isi  scopus
    5. S. D. Glyzin, A. Yu. Kolesov, N. Kh. Rozov, “Novyi podkhod k modelirovaniyu gennykh setei”, Model. i analiz inform. sistem, 26:3 (2019), 365–404  mathnet  crossref
    6. V. P. Golubyatnikov, L. S. Minushkina, “Monotonicity of the Poincaré mapping in some models of circular gene networks”, J. Appl. Industr. Math., 13:3 (2019), 472–479  mathnet  crossref  crossref  elib
    7. Glyzin S.D. Kolesov A.Yu. Rozov N.Kh., International Conference on Computer Simulation in Physics and Beyond, Journal of Physics Conference Series, 1163, ed. Shchur L., IOP Publishing Ltd, 2019  crossref  isi  scopus
    8. D. A. Bratsun, E. S. Lorgov, A. O. Poluyanov, “Repressilyator s zapazdyvayuschei ekspressiei genov. Chast I. Deterministskoe opisanie”, Kompyuternye issledovaniya i modelirovanie, 10:2 (2018), 241–259  mathnet  crossref
    9. S. D. Glyzin, A. Yu. Kolesov, N. Kh. Rozov, “An approach to modeling artificial gene networks”, Theoret. and Math. Phys., 194:3 (2018), 471–490  mathnet  crossref  crossref  mathscinet  isi  elib
    10. S. D. Glyzin, A. Yu. Kolesov, N. Kh. Rozov, “Quasi-stable structures in circular gene networks”, Comput. Math. Math. Phys., 58:5 (2018), 659–679  mathnet  crossref  crossref  isi  elib
    11. Likhoshvai V.A., Khlebodarova T.M., “On the Equivalence of Delayed Arguments and Transfer Equations For Modeling Dynamic Systems”, Vavilovskii Zhurnal Genet. Sel., 22:1 (2018), 141–144  crossref  isi  scopus
    12. S. D. Glyzin, A. Yu. Kolesov, N. Kh. Rozov, “Existence and Stability of the Relaxation Cycle in a Mathematical Repressilator Model”, Math. Notes, 101:1 (2017), 71–86  mathnet  crossref  crossref  mathscinet  isi  elib
    13. N. B. Ayupova, V. P. Golubyatnikov, M. V. Kazantsev, “On existence of a cycle in one asymmetric model of a molecular repressilator”, Num. Anal. Appl., 10:2 (2017), 101–107  mathnet  crossref  crossref  isi  elib
    14. Glyzin S.D. Kolesov A.Yu. Rozov N.Kh., “Periodic Two-Cluster Synchronization Modes in Completely Connected Genetic Networks”, Differ. Equ., 52:2 (2016), 157–176  crossref  mathscinet  zmath  isi  elib  scopus
    15. A. Yu. Kolesov, N. Kh. Rozov, V. A. Sadovnichii, “Periodic solutions of travelling-wave type in circular gene networks”, Izv. Math., 80:3 (2016), 523–548  mathnet  crossref  crossref  mathscinet  zmath  adsnasa  isi  elib
    16. S. D. Glyzin, A. Yu. Kolesov, N. Kh. Rozov, “Buffering in cyclic gene networks”, Theoret. and Math. Phys., 187:3 (2016), 935–951  mathnet  crossref  crossref  mathscinet  adsnasa  isi  elib
    17. A. S. Kornienko, “Struktura funktsionalnykh grafov dlya tsirkulyantov s lineinymi bulevymi funktsiyami v vershinakh”, PDM, 2014, no. 1(23), 84–95  mathnet
    18. V. A. Likhoshvai, S. I. Fadeev, “On the shift of a regulatory signal in models of matrix synthesis”, J. Appl. Industr. Math., 7:3 (2013), 404–411  mathnet  crossref  mathscinet
    19. S. I. Fadeev, V. V. Kogai, V. V. Mironova, N. A. Omelyanchuk, V. A. Likhoshvai, “Mathematical modeling of matter distribution in cells assembling into a ring”, Num. Anal. Appl., 6:2 (2013), 151–162  mathnet  crossref  mathscinet  elib
    20. I. R. Akberdin, F. V. Kazantsev, T. V. Ermak, V. S. Timonov, T. M. Khlebodarova, V. A. Likhoshvai, “«Elektronnaya kletka»: problemy i perspektivy”, Matem. biologiya i bioinform., 8:1 (2013), 295–315  mathnet
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
    Сибирский журнал индустриальной математики
    Statistics & downloads:
    Abstract page:852
    Full-text PDF :271
    References:80
     
      Contact us:
     Terms of Use  Registration to the website  Logotypes © Steklov Mathematical Institute RAS, 2025