Abstract:
We propose a mathematical model of infection spreading among the adult population of certain region. The model is constructed on the basis of some delay differential equations that are supplemented with integral equations of convolution type and the initial data. The variables included in the integral equations and the delay variables take into account the number of individuals in different groups and the transition rate of individuals between the groups which reflects the stages of the disease. Some properties of the solutions of the model are under study including the existence, uniqueness, and nonnegativity of the solution components on the half-axis, as well as the presence and stability of the equilibrium states. We formulate and solve the problem of eliminating infection during finite time. The time for infection eradication is estimated on using the exponentially decreasing component-by-component estimates of the solution. Also we present the results of computational experiments on estimating the eradication time and evaluating the effectiveness of the process of diagnosis and identification of sick (infected) individuals through the procedure of regular medical examinations.
Keywords:
stage-dependent epidemic model, delay differential equation, convolution integral equations, equilibrium state stability, exponentially decreasing estimate of model solution, basic reproductive number, infection eradication.
.
N. V. Pertsev and K. K. Loginov were supported by the Russian Foundation for
Basic Research (project no. 18-29-10086). V. A. Topchii was supported by the State Task to the
Sobolev Institute of Mathematics (project no. 0314-2019-0009).
Citation:
N. V. Pertsev, K. K. Loginov, V. A. Topchii, “Analysis of an epidemic mathematical model based on delay differential equations”, Sib. Zh. Ind. Mat., 23:2 (2020), 119–132; J. Appl. Industr. Math., 14:2 (2020), 396–406
\Bibitem{PerLogTop20}
\by N.~V.~Pertsev, K.~K.~Loginov, V.~A.~Topchii
\paper Analysis of an epidemic mathematical model based on delay differential equations
\jour Sib. Zh. Ind. Mat.
\yr 2020
\vol 23
\issue 2
\pages 119--132
\mathnet{http://mi.mathnet.ru/sjim1092}
\crossref{https://doi.org/10.33048/SIBJIM.2020.23.209}
\elib{https://elibrary.ru/item.asp?id=45512114}
\transl
\jour J. Appl. Industr. Math.
\yr 2020
\vol 14
\issue 2
\pages 396--406
\crossref{https://doi.org/10.1134/S1990478920020167}
\scopus{https://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85087777242}
Linking options:
https://www.mathnet.ru/eng/sjim1092
https://www.mathnet.ru/eng/sjim/v23/i2/p119
This publication is cited in the following 3 articles:
N. V. Pertsev, V. A. Topchii, K. K. Loginov, “Stokhasticheskoe modelirovanie epidemicheskogo protsessa na osnove stadiya-zavisimoi modeli s nemarkovskimi ogranicheniyami dlya individuumov”, Matem. biologiya i bioinform., 18:1 (2023), 145–176
A. D. Polyanin, V. G. Sorokin, “REShENIYa LINEINYKh NAChALNO-KRAEVYKh ZADACh REAKTsIONNO-DIFFUZIONNOGO TIPA S ZAPAZDYVANIEM”, Vestnik, 12:3 (2023), 153
N. V. Pertsev, “Construction of Exponentially Decreasing Estimates of Solutions to a Cauchy Problem For Some Nonlinear Systems of Delay Differential Equations”, Sib. Electron. Math. Rep., 18 (2021), 579–598