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Reviews
Protein synthesis as an object of physical and mathematical research and modeling
Yu. N. Zhuravleva, M. A. Guzevb, A. I. Gudimenkob a Institute of Biology and Soil Science, FEB RAS,
159, 100 let Vladivostoku ave.,
Vladivostok, 690022, Russia
b Institute for Applied Mathematics, FEB RAS,
7, Radio str.,
Vladivostok, 690041, Russia
Abstract:
The multidisciplinary analysis of the structure of a biological object reveals that the set of parameters for its description in the context of the genetic code only is not complete. On the other hand, conversion — a key event in the protein synthesis — has no analogues in classical physics and mathematics. Conversion is being discovered in a detailed analysis of transcription-translation transition in terms of fiber bundles theory. It represents a heterotopic transition that hides the analytical connection of the objects of this morphism. The introduction of a parameter of movement is fruitful when modeling the developing systems thus nesting the system into ${n+1}$-dimensional space. These aspects promote the revising the concept of organizing center in protein synthesis and ribosome work.
Keywords:
protein synthesis, mathematical modeling, fiber bundles.
Received January 20, 2019, published March 11, 2019
Citation:
Yu. N. Zhuravlev, M. A. Guzev, A. I. Gudimenko, “Protein synthesis as an object of physical and mathematical research and modeling”, Sib. Èlektron. Mat. Izv., 16 (2019), 340–368
Linking options:
https://www.mathnet.ru/eng/semr1063 https://www.mathnet.ru/eng/semr/v16/p340
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Abstract page: | 441 | Full-text PDF : | 201 | References: | 36 |
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