Aliphatic fluorine-containing amino acids

Data on the methods for synthesis of fluorine-substituted analogues of the natural aliphatic amino acids are systematised in the review. The increased interest in these amino acids is explained by the wide spectrum of their biological action and also by the possibility of using them to solve theoretical and practical problems in medicine, biochemistry, enzymology, biotechnology and other related scientific areas. Particular attention is paid in the review to preparative methods of synthesis of the fluorine-containing aliphatic amino acids and to the means of obtaining these compounds in an optically pure state. The bibliography contains 120 references.