|
This article is cited in 29 scientific papers (total in 29 papers)
β-Fluoro-substituted aminoacids
V. P. Kukhar', Yu. L. Yagupol'skii, V. A. Soloshonok Institute of Bioorganic Chemistry of Ukrainian Academy of Sciences, Kyiv
Abstract:
The review gives a systematic account of data concerning the methods of synthesis of α-, β-, and γ-aminoacids containing fluorine atoms in the β-position relative to the aminogroup. The interest in these compounds is in many respects due to the fact that most of them have proved to be highly selective irreversible inhibitors of pyridoxal-5-phosphate-dependent enzymes acting via the "suicide-substrate" mechanism. Attention is concentrated on β-fluoro-derivatives of natural α-aminoacids. The bibliography includes 114 references.
Citation:
V. P. Kukhar', Yu. L. Yagupol'skii, V. A. Soloshonok, “β-Fluoro-substituted aminoacids”, Usp. Khim., 59:1 (1990), 149–175; Russian Chem. Reviews, 59:1 (1990), 89–102
Linking options:
https://www.mathnet.ru/eng/rcr790https://doi.org/10.1070/RC1990v059n01ABEH003512 https://www.mathnet.ru/eng/rcr/v59/i1/p149
|
Statistics & downloads: |
Abstract page: | 84 |
|