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This article is cited in 20 scientific papers (total in 20 papers)
Advances in the synthesis of imidazo[1,5-a]- and imidazo[1,2-a]quinoxalines
V. A. Mamedov, A. A. Kalinin A. E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences, Kazan
Abstract:
This review is intended to generalize and systematize available information on the synthesis of imidazo[1,5-a]- and imidazo[1,2-a]quinoxalines. Relevant studies published in the last 10–15 years, as well as earlier studies less familiar to the broad chemical community, are surveyed. Major methods of formation of the imidazoquinoxaline system from substituted quinoxalines and imidazoles according to the type of bond being formed are presented. Special focus is placed on the radically new methods that enable the synthesis of various derivatives of these heterocyclic systems from available and inexpensive reagents. The mechanisms of formation of these compounds are discussed. Information on the biological activity of imidazo[1,5-a]- and imidazo[1,2-a]quinoxalines and examples of pharmaceuticals based on them are reported.
The bibliography includes 179 references.
Received: 11.07.2013
Citation:
V. A. Mamedov, A. A. Kalinin, “Advances in the synthesis of imidazo[1,5-a]- and imidazo[1,2-a]quinoxalines”, Usp. Khim., 83:9 (2014), 820–847; Russian Chem. Reviews, 83:9 (2014), 820–847
Linking options:
https://www.mathnet.ru/eng/rcr713https://doi.org/10.1070/RC2014v083n09ABEH004424 https://www.mathnet.ru/eng/rcr/v83/i9/p820
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